Application of Preoperative CT/MRI Image Fusion in Target Positioning for Deep Brain Stimulation / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
; (4): 161-167, 2016.
Article
em En
| WPRIM
| ID: wpr-281468
Biblioteca responsável:
WPRO
ABSTRACT
<strong>Objective</strong> To explore the efficacy of target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation.<strong>Methods</strong> We retrospectively analyzed the clinical data and images of 79 cases (68 with Parkinson's disease, 11 with dystonia) who received preoperative CT/MRI image fusion in target positioning of subthalamic nucleus in deep brain stimulation. Deviation of implanted electrodes from the target nucleus of each patient were measured. Neurological evaluations of each patient before and after the treatment were performed and compared. Complications of the positioning and treatment were recorded.<strong>Results</strong> The mean deviations of the electrodes implanted on X, Y, and Z axis were 0.5 mm, 0.6 mm, and 0.6 mm, respectively. Postoperative neurologic evaluations scores of unified Parkinson's disease rating scale (UPDRS) for Parkinson's disease and Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) for dystonia patients improved significantly compared to the preoperative scores (P<0.001); Complications occurred in 10.1% (8/79) patients, and main side effects were dysarthria and diplopia.<strong>Conclusion</strong> Target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation has high accuracy and good clinical outcomes.
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Base de dados:
WPRIM
Assunto principal:
Doença de Parkinson
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Terapêutica
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Imageamento por Ressonância Magnética
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Tomografia Computadorizada por Raios X
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Estudos Retrospectivos
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Estimulação Encefálica Profunda
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Distonia
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Métodos
Tipo de estudo:
Observational_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article