Progress in the effects of injury and regeneration of gustatory nerves on the taste functions in animals / 生理学报
Acta Physiologica Sinica
; (6): 519-527, 2014.
Article
em Zh
| WPRIM
| ID: wpr-297463
Biblioteca responsável:
WPRO
ABSTRACT
The sensor of the taste is the taste bud. The signals originated from the taste buds are transmitted to the central nervous system through the gustatory taste nerves. The chorda tympani nerve (innervating the taste buds of the anterior tongue) and glossopharyngeal nerve (innervating the taste buds of the posterior tongue) are the two primary gustatory nerves. The injuries of gustatory nerves cause their innervating taste buds atrophy, degenerate and disappear. The related taste function is also impaired. The impaired taste function can be restored after the gustatory nerves regeneration. The rat model of cross-regeneration of gustatory nerves is an important platform for research in the plasticity of the central nervous system. The animal behavioral responses and the electrophysiological properties of the gustatory nerves have changed a lot after the cross-regeneration of the gustatory nerves. The effects of the injury, regeneration and cross-regeneration of the gustatory nerves on the taste function in the animals will be discussed in this review. The prospective studies on the animal model of cross-regeneration of gustatory nerves are also discussed in this review. The study on the injury, regeneration and cross-regeneration of the gustatory nerves not only benefits the understanding of mechanism for neural plasticity in gustatory nervous system, but also will provide theoretical basis and new ideas for seeking methods and techniques to cure dysgeusia.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fisiologia
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Paladar
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Papilas Gustativas
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Língua
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Nervo da Corda do Tímpano
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Nervo Glossofaríngeo
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Regeneração Nervosa
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Plasticidade Neuronal
Tipo de estudo:
Observational_studies
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2014
Tipo de documento:
Article