Updated roles of adrenergic receptors in prostate cancer / 中华男科学杂志
National Journal of Andrology
; (12): 372-376, 2014.
Article
em Zh
| WPRIM
| ID: wpr-309703
Biblioteca responsável:
WPRO
ABSTRACT
Adrenergic receptors are members of the G-protein coupled receptor superfamily. Recent studies revealed that these adrenergic receptors are playing an important role in the growth and metastasis of prostate cancer cells. The expression of adrenergic receptors rises significantly in prostate cancer cells and tissues. Agonists of these receptors promote the growth and mobility of prostate cancer cells, while antagonists may suppress their proliferation, trigger their apoptosis, and inhibit their metastasis. Clinically, receptor antagonists can significantly reduce the risk of prostate cancer and improve its prognosis after androgen depravation therapy. This article presents an overview on the roles of adrenergic receptors in prostate cancer.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Patologia
/
Farmacologia
/
Fisiologia
/
Neoplasias da Próstata
/
Receptores Adrenérgicos
/
Apoptose
/
Antagonistas Adrenérgicos
/
Agonistas Adrenérgicos
/
Metabolismo
Limite:
Humans
/
Male
Idioma:
Zh
Ano de publicação:
2014
Tipo de documento:
Article