Effect of Runing II on expression of vascular endothelial growth factor in transplanted tumor of mammary cancer MA-891 in TA2 mice / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 251-253, 2004.
Article
em Zh
| WPRIM
| ID: wpr-326780
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of Runing II on expression of vascular endothelial growth factor (VEGF) in transplanted tumor of mammary cancer MA-891 in TA2 mice.</p><p><b>METHODS</b>The MA-981 mice mammary cancer cell cultivated in vivo was inoculated into the right axilla subcutaneously of TA2 mice to establish the transplanted tumor model, which were treated with Runing II.</p><p><b>RESULTS</b>Runing II could inhibit the growth of transplanted tumor and the occurrence of lung metastasis (P < 0.05), reduce the expression of VEGF protein and mRNA in tumor tissue (P < 0.05).</p><p><b>CONCLUSION</b>Runing II could reduce the expression of VEGF protein and mRNA, hence to inhibit the growth of tumor and lung metastasis.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Farmacologia
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RNA Mensageiro
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Medicamentos de Ervas Chinesas
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Reação em Cadeia da Polimerase Via Transcriptase Reversa
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Fator A de Crescimento do Endotélio Vascular
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Genética
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Neoplasias Mamárias Experimentais
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Metabolismo
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Transplante de Neoplasias
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Antineoplásicos Fitogênicos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2004
Tipo de documento:
Article