Study on treatment effectiveness and safety in children with chronic hepatitis B or C using bicyclo tablets / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 380-382, 2005.
Article
em Zh
| WPRIM
| ID: wpr-333001
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>To evaluate treatment effectiveness and safety of bicyclo tablets in children with chronic hepatitis B or C.</p><p><b>METHODS</b>A randomized controlled trial was conducted in 148 children with chronic hepatitis B or C for evaluating safety, tolerability, and efficacy of treatment with bicyclo tablets or Hugan tablets. Children in therapy group were treated with bicyclo tablets and control group treated with Hugan tablets.</p><p><b>RESULTS</b>(1) ALT and AST level decreased more prominently in therapy group than in control group (P<0.01). (2) Bicyclo was more effective than Hugan tablets (P<0.01). (3) Symptoms were ameliorated more prominently in bicyclo group than in control group (P<0.01). (4) Both groups had no significant adverse events.</p><p><b>CONCLUSION</b>Satisfactory therapeutic effect and safety were obtained with bicyclo tablets in children with chronic hepatitis B or C.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Comprimidos
/
Compostos de Bifenilo
/
Resultado do Tratamento
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Hepatite B Crônica
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Hepatite C Crônica
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Usos Terapêuticos
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Tratamento Farmacológico
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
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Child
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Child, preschool
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Humans
Idioma:
Zh
Ano de publicação:
2005
Tipo de documento:
Article