Successful Localization of Distant Metastasis in Parathyroid Carcinoma Using Intraoperative Parathyroid Hormone Assay
Endocrinology and Metabolism
; : 92-96, 2011.
Article
em Ko
| WPRIM
| ID: wpr-34096
Biblioteca responsável:
WPRO
ABSTRACT
Intra-operative parathyroid hormone (IOPTH) assay is a useful tool to confirm complete excision of all hyper-functioning parathyroid gland tissue. In this report, we describe a case with successful localization of distant metastasis in a patient with parathyroid carcinoma using the IOPTH assay. A 53-year-old man presented to our clinic with a serum calcium level of 11.8 mg/dL and an intact PTH level of 233.3 pg/mL. He had been treated for parathyroid carcinoma eleven years ago. Two suspected metastatic lesions were detected on the chest computed tomography. Due to the vastly different surgical field necessary to excise each lesion, we preferentially removed only one lesion and we monitored the other remaining suspected lesion without resection via IOPTH assay. Six months later, the patient's serum calcium and intact PTH levels remained within their normal ranges. To the best of our knowledge, this is the first case to effectively utilize IOPTH assay for the management of metastatic parathyroid carcinoma.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Hormônio Paratireóideo
/
Neoplasias das Paratireoides
/
Glândulas Paratireoides
/
Valores de Referência
/
Tórax
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Cálcio
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Metástase Neoplásica
Limite:
Humans
Idioma:
Ko
Ano de publicação:
2011
Tipo de documento:
Article