A Case of Autoimmune Hepatitis Combined with Ulcerative Colitis / 대한내과학회지

ABSTRACT

Autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and primary biliary cirrhosis (PBC) are the major immune-mediated chronic liver diseases. They are characterized by circulating autoantibodies, hypergammaglobulinemia, unique clinical features, and associations with other autoimmune diseases, such as inflammatory bowel disease and autoimmune thyroiditis. Primary biliary cirrhosis is known to be associated with inflammatory bowel disease, such as ulcerative colitis. On the other hand, autoimmune hepatitis is rarely associated with ulcerative colitis. Here, we report a case diagnosed as autoimmune hepatitis combined with ulcerative colitis on the basis of histological and endoscopic findings.