Clinical analysis of 19 cases of uterine sarcoma / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
; : 342-349, 2005.
Article
em Ko
| WPRIM
| ID: wpr-39145
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE: The aim is to evaluate the clinical findings of uterine sarcoma we had experienced. METHODS: This study was retrospectively reviewed 19 patients with uterine sarcoma who were managed at Wonju Christian Hospital between September 1982 and May 2003. We analyzed clinical features, type of surgery, adjuvant therapy, three year-survival rate, prognostic factors of uterine sarcoma, and the effects of postoperative chemotherapy and radiotherapy on death. RESULTS: Our study included four histologic types: 8 patients with leiomyosarcoma (42.1%), 5 patients with endometrial stromal sarcoma (26.3%), 4 patients with malignant mixed Mullerian tumor (21.0%), 1 patient with angiosarcoma (5.3%) and 1 patient with both leiomyosarcoma and endometrial stromal sarcoma (5.3%) (Table 1). The cases were classified according to the FIGO staging system. 13 patients (63.2%) had stage I, 2 patients (10.5%) stage II, 2 patients (10.5%) stage III, 3 patients (15.8%) stage IV (Table 1). The three-year survival rate of uterine sarcoma was 53.8%, the most common symptom was abnormal vaginal bleeding. CONCLUSION: Uerine sarcomas are aggressive tumors with poor prognosis, except when the diagnosis is low grade endometrial stromal sarcoma. The effects of postoperative chemotherapy and radiotherapy on death were not statistically significant. This is a retrospective review with small numbers and short periods. Prospective multicentric trials including a statistically evaluable number of patients are necessary.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prognóstico
/
Radioterapia
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Sarcoma
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Hemorragia Uterina
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Taxa de Sobrevida
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Estudos Retrospectivos
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Sarcoma do Estroma Endometrial
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Diagnóstico
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Tratamento Farmacológico
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Leiomiossarcoma
Tipo de estudo:
Diagnostic_studies
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Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
Ko
Ano de publicação:
2005
Tipo de documento:
Article