Single Institutional Experiences of Insulinoma
Journal of the Korean Surgical Society
; : 128-132, 2007.
Article
em Ko
| WPRIM
| ID: wpr-44389
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: We present our experiences of pancreatic insulinoma among the functioning neuroendocrine neoplasm of the pancreas, to review the natural history and suggest proper management. METHODS: From June 1990 to August 2006, patients with diagnosis of pancreatic insulinoma were retrospectively reviewed. RESULTS: Thirteen patients (5 men and 8 women) with median age of 42 years (range, 12~68 years) were investigated. One patient (12%) with pancreatic insulinoma was MEN 1. Intraoperative ultrasound scan (sensitivity, 88%) was the most powerful modality for tumor localization. Sixteen neoplasms with median tumor size 1 cm (range, 0~3 cm) were found. Ten neoplasm (62%) were located in the heads/ necks of the pancreas. Six neoplasm (38%) were located in the tails. Five neoplasm (31%) were located around the neck areas near the SMV or PV. Twelve patients (92%) underwent enucleation, and two patients (15%) underwent distal pancreatectomy with splenectomy. 100% of patients with pancreatic insulinoma have survived and the overall disease free 10-year survival was found to be about 85.7%. CONCLUSION: Exact localization of tumor by intraoperative ultrasound and effective surgical removal can be significantly beneficial for good prognosis.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pâncreas
/
Pancreatectomia
/
Prognóstico
/
Esplenectomia
/
Estudos Retrospectivos
/
Ultrassonografia
/
Neoplasia Endócrina Múltipla Tipo 1
/
História Natural
/
Diagnóstico
/
Insulinoma
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
/
Male
Idioma:
Ko
Ano de publicação:
2007
Tipo de documento:
Article