Akt inhibitors in the treatment of colorectal cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 224-227, 2015.
Article
em Zh
| WPRIM
| ID: wpr-464957
Biblioteca responsável:
WPRO
ABSTRACT
Protein kinase B( Akt)is an intermediate signal molecule in PI3K-Akt-mTOR signaling pathway which plays an important role in development and incidence of colorectal cancer when activated by phosphorylation. As target of drugs,Akt has become a focus in the treatment of colorectal cancer. Clinical trials research proves that many kinds of Akt inhibitors have good antitumor activity. In recent years,the Akt inhibi-tors are more and more be taken seriously in colorectal cancer treatment.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Ano de publicação:
2015
Tipo de documento:
Article