Focal Segmental Glomerulosclerosis in a Child with Prader-Willi Syndrome: A Case of Obesity-associated Focal Segmental Glomerulosclerosis
Journal of the Korean Society of Pediatric Nephrology
; : 244-249, 2004.
Article
em En
| WPRIM
| ID: wpr-46790
Biblioteca responsável:
WPRO
ABSTRACT
Obesity-associated focal segmental glomerulosclerosis(OB-FSGS) has been known to progress into advanced renal insufficiency, and its clinicopathological features include obesity, FSGS lesions with glomerulomegaly and, nephrotic-range proteinuria without edema. A 14- year old girl with Prader-Willi syndrome showed nephrotic-range proteinuria without hypoalbuminemia or edema. The renal biopsy revealed focal segmental glomerulosclerosis together with glomerular hypertrophy and an increased mesangial matrix. We report here a case of OB-FSGS as one of the renal problems of Prader-Willi syndrome, and we came to the conclusion that Prader-Willi syndrome is one of the possible disease entities that can lead to renal insufficiency through obesity.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Síndrome de Prader-Willi
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Proteinúria
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Biópsia
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Glomerulosclerose Segmentar e Focal
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Hipoalbuminemia
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Edema
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Insuficiência Renal
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Hipertrofia
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Obesidade
Limite:
Child
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Female
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Humans
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article