A case of Epstein-Barr virus-positive primary cutaneous diffuse large B-cell lymphoma of the elderly / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12): 501-503, 2016.
Article
em Zh
| WPRIM
| ID: wpr-494833
Biblioteca responsável:
WPRO
ABSTRACT
An 88?year?old man presented with multiple nodules and ulcers on both lower limbs for 6 months. Dermatological examination showed multiple dark purple hard nodules with central crusted ulceration. Histopathological examination revealed a diffuse infiltration of atypical lymphoid cells with large hyperchromatic nuclei in the dermis and subcutis, as well as small necrotic foci in some regions. Conspicuous mitoses were seen. The large lymphoid cells were positive for CD20, CD79a and Bcl?2. Epstein?Barr virus?encoded RNA was detected by in situ hybridization. These findings were consistent with Epstein?Barr virus?positive diffuse large B?cell lymphoma. The patient gave up systemic chemotherapy and died six months later.
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Base de dados:
WPRIM
Idioma:
Zh
Ano de publicação:
2016
Tipo de documento:
Article