Clinical Manifestations and Prognostic Factors of IgA Nephropathy with Long-Term Follow-Up / 대한내과학회지
Korean Journal of Medicine
; : 46-53, 2015.
Article
em Ko
| WPRIM
| ID: wpr-49744
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS:
Immunoglobulin A nephropathy (IgAN) is the most common type of primary glomerulonephritis worldwide. Although several studies have identified IgAN prognostic factors in Korea, the follow-up period was insufficient to evaluate the natural history of IgAN.METHODS:
A total of 471 patients were diagnosed with IgAN after percutaneous renal biopsy between April 1985 and March 2003. Patients with secondary IgAN and patients with a follow-up 1.3 mg/dL, estimated glomerular filtration rate or = 1 g/day, and severe renal pathology by the Haas sub-classification were significantly associated with ESRD. When these factors were included in multivariate Cox regression analyses, only severe renal pathology by the Haas sub-classification was an independent prognostic factor for IgAN.CONCLUSIONS:
Careful follow-up and treatment is recommended, particularly in patients with IgAN and severe renal pathology by the Haas sub-classification.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Patologia
/
Prognóstico
/
Proteinúria
/
Biópsia
/
Albumina Sérica
/
Taxa de Sobrevida
/
Seguimentos
/
História Natural
/
Creatinina
/
Diagnóstico
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Female
/
Humans
/
Male
País como assunto:
Asia
Idioma:
Ko
Ano de publicação:
2015
Tipo de documento:
Article