Effects of Lung Recruitment Maneuvers in Patients with Acute Respiration Distress Syndrome / 中国医师杂志

ABSTRACT

Objective To investigate the clinical effects, therapy safety and maintenance time of recruitment maneuvers (RM) combined with lung protective strategy in patients with acute respiratory distress syndrome (ARDS). Methods Thirty-two ventilated patients with ARDS underwent RM using a pressure of 30cmH_2O for 30s, without any sedatives and neuromuscular blocking agents. Results Compared with before RM, both oxhemoglobin saturation measured by pulse oximetry (SpO_2) and partial pressure of arterial oxygen (PaO_2) were significantly increased during one hour after applying RM. SpO_2 increased significantly within two hours after RM. The peak inspiratory pressures (PIP), heart rate (HR) and Pplateau inspiratory pressures (Pplate) had not significant difference between after and before RM, but respiratory system compliance (Crs) increased markedly in one hour after RM (P