Effects of heterogously-expressed RON receptor tyrosine kinase on motile/invasive ability of human colorectal cancer cell line RKO / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)1989.
Article
em Zh
| WPRIM
| ID: wpr-527891
Biblioteca responsável:
WPRO
ABSTRACT
AIM: To investigate the roles of overexpression of RON receptor tyrosine kinase in motile/invasive ability of human colorectal cancer cell line RKO.METHODS: A eucaryotic expression vector pDR2 containing full-length wt-RON cDNA was transfected into the colorectal cancer cell line RKO and a stable expression clone was obtained.The motile/invasive ability was tested by wound healing test and the transwell migration assay.The expression of E-cadherin was measured by Western blotting.RESULTS: Motile ability of transfected RKO was greatly promoted by transwell chemotaxis assay(P
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WPRIM
Idioma:
Zh
Ano de publicação:
1989
Tipo de documento:
Article