Determination of Fluvastatin Sodium Extended-release Tablets by HPLC / 中国药房
China Pharmacy
; (12)2007.
Article
em Zh
| WPRIM
| ID: wpr-529709
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To establish a HPLC method for determining the content of fluvastatin sodium in fluvastatin sodium extended-release tablets.METHODS:
An Agilent SB-C18 column was used and the mobile phase was CH3CN-0.1% phosphate acid, 50∶50. Flow rate was 1mL?min-1, wavelength was 234nm and the sample size was 20?L.RESULTS:
The fluvastatin sodium concentration had good liner relationship from 4.84~96.8?g?mL-1(r=0.999 9), and the average recovery was 100.1%,RSD=0.9%.CONCLUSION:
This method was simple, fast, accurate, and precise, could be used to determine content in fluvastatin sodium extended-release tablets.
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Base de dados:
WPRIM
Idioma:
Zh
Ano de publicação:
2007
Tipo de documento:
Article