Influence on cellular apoptosis and telomerase activity in bladder cancer treated with BCG-CWS and IL-2 / 中华泌尿外科杂志
Chinese Journal of Urology
; (12)2000.
Article
em Zh
| WPRIM
| ID: wpr-536326
Biblioteca responsável:
WPRO
ABSTRACT
Objective To study the cellular apoptosis and telomerase activity in bladder cancer before and after treatment with cell wall skeleton of bacillus Calmett Guerin(BCG CWS) and interleukin 2(IL 2). Methods The cellular apoptosis and telomerase activity of 33 cases of bladder cancer tissues were detected by terminal deoxynucleotidyl transferase mediated dUTP biotin nick end labeling(TUNEL) and telomeric repeat amplification protocol(TRAP) assay both before and after treated with BCG CWS and IL 2. Results The apoptosis index for bladder cancers before and after treatment with BCG CWS and IL 2 was (35.6?12.7)% and (79.1?11.3)% respectively, the apoptosis index being obviously increased after the treatments, P
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Base de dados:
WPRIM
Tipo de estudo:
Guideline
Idioma:
Zh
Ano de publicação:
2000
Tipo de documento:
Article