The effect of PostGraft(TM) on implants were installed at the tibia of ovariectomized rats / 대한치과보철학회지

ABSTRACT

PURPOSE: This study evaluated PostGraft(TM) which enhances implant stability and bone density. MATERIALS AND METHODS: Forty eight implants were installed at the tibia of ovariectomized rats. The group administrated with PostGraft(TM) was the experimental group, and the control group was not administrated. Implant stability was evaluated at the 2nd, 4th and 6th week by Periotest value, bone mineral density, bone-to-implant contact. These values were analyzed statistically with Mann-Whitney U test (P<.05). Histological analysis was evaluated at the 2nd, 4th and 6th week. RESULTS: According to the Periotest(R) measurement, both experimental and control groups showed decrease in values as time elapsed. Greater decrease was observed in the experimental group but there was no significant difference. By examining the radiographic images, both experimental and control groups showed tendency of increase in bone density. Greater increase was seen in the experimental group but there was no significant difference. According to the bone-to-implant contact measurement, both experimental and control groups showed increase in values as time elapsed. Greater increase was seen in the experimental group. At the 2nd and 4th week, there was no significant difference. But at the 6th week, there was significant difference (P<.05). By histological analysis, both experimental and control groups showed increase in bone formation as time elapsed. In addition, greater increase was seen in the experimental group. CONCLUSION: It could be concluded that the PostGraft(TM) medicated group showed better results in the bone density and osseointegration.