Pathogenic Role of Glutamic Acid in Tourette's Syndrome / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)1992.
Article
em Zh
| WPRIM
| ID: wpr-638378
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the effect of glutamic acid (monosodium glutamate,MSG) on Tourette's syndrome (TS). Methods These rats were divided into 2 groups: one group with acute intracerebroventricularly injection (ICV) of MSG or artificial cerebrospinal fluid (CSF), and another group with chronic administration of MSG in a dose of 40 mg/kg in drinking water everyday. Observers who were blind to the two- part subjects assessed the scores of TS- like stereotyped locomotion. Results 1. These groups of 100 ?g or 200 ?g glutamic acid may induce significant TS - like stereotyped locomotion ( P
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Base de dados:
WPRIM
Idioma:
Zh
Ano de publicação:
1992
Tipo de documento:
Article