Gene Therapy for Bone Tissue Engineering
Tissue Engineering and Regenerative Medicine
; (6): 111-125, 2016.
Article
em En
| WPRIM
| ID: wpr-646906
Biblioteca responsável:
WPRO
ABSTRACT
Gene therapy holds a great promise and has been extensively investigated to improve bone formation and regeneration therapies in bone tissue engineering. A variety of osteogenic genes can be delivered by combining different vectors (viral or non-viral), scaffolds and delivery methodologies. Ex vivo & in vivo gene enhanced tissue engineering approaches have led to successful osteogenic differentiation and bone formation. In this article, we review recent advances of gene therapy-based bone tissue engineering discussing strengths and weaknesses of various strategies as well as general overview of gene therapy.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Osteogênese
/
Regeneração
/
Osso e Ossos
/
Terapia Genética
/
Proteínas Morfogenéticas Ósseas
/
Engenharia Tecidual
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article