Association of resting heart rate and coronary artery lesions with left ventricular function in coronary heart disease / 实用医学杂志

ABSTRACT

Objective To explore the association of resting heart rate (RHR) and coronary artery lesions with left ventricular function in coronary heart disease for secondary prevention of this disorder.Methods We collected data on 239 patients with coronary heart disease confirmed by coronary angiography or coronary CTA examination in Military General Hospital of Guangzhou Command from January 2016 to August 2017.The clinical data and results of selective coronary angiography were studied.According to baseline RHR,the patients were divided into 4 groups with RHR ＜ 60 min (group A,32 cases),60 to 69 min (group B,60 cases),70 to 79 min (group C,68 cases),and ≥ 80 min (group D,79 cases) for analyzing the relationship of RHR with coronary artery lesions and left ventriculai function,and investigating the association of RHR and left ventricular indexes with severity of coronary artery lesions by ordinal Logistic regression analysis.Results Coronary artery lesions differed significantly among the 4 groups (P ＜ 0.05).the difference of LVDs、LVDd、LAs and EF was statistically significant (P ＜ 0.05),but there was no difference of LAd (P ＞ 0.05).Smoking、diabetes、the index of EF and LVDs were found to correlate with the degree of coronary lesion by Logistic regression analysis (P ＜ 0.05).Conclusions RHR can affect the severity of coronary artery disease and left ventricular function in patients with coronary heart disease,and good control of RHR is beneficial for the prognosis of patients with coronary heart disease.Smoking、diabetes、the index of EF and LVDs were found to correlate with the degree of coronary lesion by Logistic regression analysis (P ＜ 0.05).