Molecular mechanism of alcohol-associated gastric cancer / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 906-909, 2018.
Article
em Zh
| WPRIM
| ID: wpr-705151
Biblioteca responsável:
WPRO
ABSTRACT
Gastric cancer is the second most common cancer in China. Alcohol consumption is related to gastric cancer as a sig-nificant risk factor. Some key enzymes is expected to influence the alcohol-associated metabolism. There are many molecular mechanisms of alcohol-related gastric cancer, such as generation of acetaldehyde by microbiome, inflammation, up-regulation of Pol Ⅲ genes, carcinogen-DNA adduct formation and genetic polymorphisms of alcohol metabolizing enzymes. Different types and concentrations of alcohol have different effects on the devel-opment of gastric cancer. This review presents a systematic ex-position on the molecular mechanism of alcohol-associated gastric cancer.
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1
Base de dados:
WPRIM
Tipo de estudo:
Risk_factors_studies
Idioma:
Zh
Ano de publicação:
2018
Tipo de documento:
Article