Gynecomastia induced by H1-antihistamine (ebastine) in a patient with idiopathic anaphylaxis
Asia Pacific Allergy
; (4): 187-190, 2015.
Article
em En
| WPRIM
| ID: wpr-750027
Biblioteca responsável:
WPRO
ABSTRACT
H1-antihistamine is generally a well-tolerated and safe drug. However, in resemblance with all other drugs, H1-antihistamines can also prompt adverse drug reactions (ADRs). We recently encountered the very unusual ADR of H1-antihistamine-induced gynecomastia. A 21-year-old man with idiopathic anaphylaxis was treated with ebastine (Ebastel), a second-generation H1-antihistamine, for the prevention of anaphylaxis. Three months later, the patient remained well without anaphylaxis, but had newly developed gynecomastia. Because anaphylaxis recurred after the cessation of H1-antihistamine, the preventive medication was changed to omalizumab. A few months later, his gynecomastia had entirely disappeared. Physicians should be aware of this exceptional ADR of H1-antihistamine.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Omalizumab
/
Ginecomastia
/
Antagonistas dos Receptores Histamínicos H1
/
Anafilaxia
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article