Trends in contralateral prophylactic mastectomy rate according to clinicopathologic and socioeconomic status
Annals of Surgical Treatment and Research
; : 113-118, 2019.
Article
em En
| WPRIM
| ID: wpr-762699
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) among women diagnosed with unilateral breast cancer or mutations in BRCA1 or BRCA2 to reduce the occurrence of contralateral breast cancer. This study aimed to examine trends in the CPM rate according to clinicopathologic and socioeconomic status at a single institution in Korea. METHODS: This study included 128 patients with mutations in BRCA1 or BRCA2. Patients were divided into a CPM group (n = 8) and a non-CPM group (n = 120) between May 2013 and March 2016. The main outcome variables, including epidemiology, clinical features, socioeconomic status, and tumor characteristics, were analyzed. RESULTS: A total of 8 CPMs were performed among 128 patients. All CPM patients were married. The proportion of professional working women was higher in the CPM group (P = 0.049). Most patients who underwent CPM graduated college, compared to less than a third of the non-CPM group (P = 0.013). The CPM group had a higher rate of visits to the Hereditary Breast and Ovarian Cancer (HBOC) clinic (P = 0.021). The risk-reducing salpingo-oophorectomy (RRSO) rate was significantly higher in the CPM group (P < 0.01). CONCLUSION: CPM rates were significantly different according to socioeconomic status. The CPM rate tends to increase in highly educated and professional working women. The socioeconomic status of patients is an important factor in the decision to participate in the HBOC clinic and undergo CPM or RRSO.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Neoplasias Ovarianas
/
Classe Social
/
Mulheres Trabalhadoras
/
Mama
/
Neoplasias da Mama
/
Epidemiologia
/
Neoplasias Unilaterais da Mama
/
Coreia (Geográfico)
/
Mastectomia
Tipo de estudo:
Prognostic_studies
Limite:
Female
/
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article