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Interleukin-1β is a potential therapeutic target for periodontitis: a narrative review / 国际口腔科学杂志·英文版
Article em En | WPRIM | ID: wpr-781380
Biblioteca responsável: WPRO
ABSTRACT
Interleukin(IL)-1β, a pro-inflammatory cytokine, was elevated and participates in periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical evidence, but also the increased IL-1β triggers a series of inflammatory reactions and promotes bone resorption. Currently, IL-1β blockage has been therapeutic strategies for autoimmune and autoinflammatory diseases such as rheumatoid arthritis, cryopyrin-associated periodic syndromes, gout and type II diabetes mellitus. It is speculated that IL-1β be a potential therapeutic target for periodontitis. The review focuses on the production, mechanism, present treatments and future potential strategies for IL-1β in periodontitis.
Texto completo: 1 Base de dados: WPRIM Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Idioma: En Ano de publicação: 2020 Tipo de documento: Article