Bilateral Renal Metastasis of Hürthle Cell Thyroid Cancer with Discordant Uptake Between I-131 Sodium Iodide and F-18 FDG / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
; : 256-260, 2017.
Article
em En
| WPRIM
| ID: wpr-786932
Biblioteca responsável:
WPRO
ABSTRACT
Renal metastasis of thyroid cancer is extremely rare. We report the case of a 62-year-old woman with Hürthle cell thyroid cancer (HCTC) with lungs, bones, and bilateral kidneys metastases. The renal metastatic lesions were clearly demonstrated by ¹³¹I whole body scan (WBS) with SPECT/CT. However, they exhibited false-negative results in ¹⁸F-FDG PET/CT, kidney ultrasonography, and contrast-enhanced CT scan. The findings imply that tumors have low glucose metabolism and are able to accumulate radioiodine, which is not commonly found in the relatively aggressive nature of HCTC. The patient received two sessions of 200 mCi ¹³¹I therapy within 6 months duration. There was complete treatment response as evaluated by the second post-therapeutic ¹³¹I SPECT/CT and serum thyroglobulin. To our knowledge, renal metastasis from HCTC with positive ¹³¹I but negative ¹⁸F-FDGuptake has not been reported in the literature. This case suggests that ¹³¹I SPECT/CTis useful for lesion localization and prediction of ¹³¹I therapy response.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Sódio
/
Iodeto de Sódio
/
Tireoglobulina
/
Glândula Tireoide
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Neoplasias da Glândula Tireoide
/
Tomografia Computadorizada por Raios X
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Ultrassonografia
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Imagem Corporal Total
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Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada
/
Glucose
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article