Non-cirrhotic portal hypertension in an ankylosing spondylitis patient / 영남의대학술지
Yeungnam University Journal of Medicine
; : 89-93, 2018.
Article
em En
| WPRIM
| ID: wpr-787089
Biblioteca responsável:
WPRO
ABSTRACT
Idiopathic non-cirrhotic portal hypertension (INCPH) is a disease with an uncertain etiology consisting of non-cirrhotic portal hypertension and portal pressure increase in the absence of liver cirrhosis. In INCPH, patients exhibit normal liver functions and structures. The factors associated with INCPH include the following: Umbilical/portal pyremia, bacterial diseases, prothrombic states, chronic exposure to arsenic, vinyl chloride monomers, genetic disorders, and autoimmune diseases. Approximately 70% of patients present a history of major variceal bleeding, and treatment relies on the prevention of complications related to portal hypertension. Autoimmune disorders associated with INCPH are mainly systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritis. To the best of our knowledge, a case of ankylosing spondylitis (AS) associated with INCPH has not been reported thus far. Therfore, we report our experience of a patient with AS accompanied by INCPH, who showed perisplenic varices with patent spleno-portal axis and hepatic veins along with no evidence of cirrhosis on liver biopsy, and provide a brief literature review.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Arsênio
/
Artrite Reumatoide
/
Escleroderma Sistêmico
/
Doenças Autoimunes
/
Espondilite Anquilosante
/
Varizes
/
Cloreto de Vinil
/
Biópsia
/
Fibrose
/
Varizes Esofágicas e Gástricas
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article