The prognosis factors among breast cancer patients with extensive axillary lymph node metastasis
Korean Journal of Clinical Oncology
; (2): 43-47, 2018.
Article
em En
| WPRIM
| ID: wpr-788025
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: This study was designed to retrospectively identify prognostic factors of survival among breast cancer patients with 10 or more metastatic lymph nodes (LNs).METHODS: The study included 58 patients with 10 or more metastatic LNs who received standard treatment from January 2005 to December 2015. To identify the prognostic factors, we analyzed the difference of disease-free survival (DFS) according to clinicopathologic factors.RESULTS: The 5-year DFS and overall survival rates in all patients were 55% and 69%, respectively. Tumor size, number of metastatic LNs and ratio of metastatic to total LNs were associated with poorer prognosis. DFS was significantly poorer in patients with >15 than ≤15 metastatic LNs (hazard ratio [HR], 4.60; 95% confidence interval [CI], 1.38–15.32) and with LN ratio >0.64 than ≤0.64 (HR, 26.13; 95% CI, 3.16–215.80) A scoring system based on these factors was significantly prognostic of survival outcomes.CONCLUSION: This study identified factors of survival in breast cancer patients with extensive LN metastasis. Patients with unfavorable factors may require modified management to improve their clinical outcomes.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Prognóstico
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Mama
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Neoplasias da Mama
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Taxa de Sobrevida
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Estudos Retrospectivos
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Intervalo Livre de Doença
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Linfonodos
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Metástase Linfática
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Metástase Neoplásica
Tipo de estudo:
Observational_studies
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Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article