The research progress of Gli1 in the regulation of epithelial mesenchymal transition in oral squamous cell car-cinoma / 口腔疾病防治
Journal of Prevention and Treatment for Stomatological Diseases
; (12): 327-330, 2017.
Article
em Zh
| WPRIM
| ID: wpr-822402
Biblioteca responsável:
WPRO
ABSTRACT
@#HH (hedgehog) signal pathway consists the hedgehoge ligand (Shh、Ihh and Dhh), the Patch and Smo membrane protein complex and Zinc finger transcription factor Gli (Gli1, Gli2, Gli3). In HH (hedgehog) signaling pathway, Gli1 not only plays a dominant and decisive role in the zinc finger transcription factor Gli (Glioma-associated oncogene homolog) family, but also includes epithelial-mesenchymal transition (EMT) and oral squamous cell carcinoma, tumor invasion and metastasis. The research on oral squamous cell carcinoma and Shh/Gli1 signal axis is rare. In this paper, the squamous cell carcinoma of oral epithelial mesenchymal transformation and correlation study of quality Gli1 is reviewed.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article