Clinical value of cleaved lymphocytes in assisting the diagnosis of pertussis in children / 中国当代儿科杂志

ABSTRACT

OBJECTIVE@#To study the value of cleaved lymphocytes in peripheral blood smear in assisting the early diagnosis of pertussis.@*METHODS@#Nasopharyngeal swabs and peripheral blood samples were collected from 107 children with pertussis-like disease. PCR-flow fluorescent hybridization was used to detect the nucleic acids of Bordetella pertussis. Based on the detection results, the children were divided into two groups: pertussis (n=52) and non-pertussis (n=55). According to age, the pertussis group was divided into two subgroups: 0.05).@*CONCLUSIONS@#The detection of cleaved lymphocytes combined with peripheral blood cell counts provides a new option for the early diagnosis of pertussis in children.