Role of transmembrane proteins in malignant tumors / 国际肿瘤学杂志
Journal of International Oncology
; (12): 355-359, 2020.
Article
em Zh
| WPRIM
| ID: wpr-863491
Biblioteca responsável:
WPRO
ABSTRACT
Transmembrane proteins (TMEMs) are a class of membrane proteins, also known as integral membrane proteins, that contain at least one transmembrane structure. A variety of membrane protein function has been found closely related to the proliferation, invasion and metastasis of malignant tumors TMEM48, TMEM45A/B, TMEM14A, TMEM158 and TMEM206 have tumor promoting effects; TMEM25 and TMEM7 have antitumor effects; TMEM16A, TMEM17, TMEM97, TMEM88 and TMEM176 play heterogeneity roles in different tumors. These TMEMs can be used as potential prognostic indicators and new therapeutic targets.
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Base de dados:
WPRIM
Idioma:
Zh
Ano de publicação:
2020
Tipo de documento:
Article