Progress in pathogenicity of Panton-Valentine Leukocidin produced by methicillin-resistant Staphylococcus aureus / 中华微生物学和免疫学杂志

ABSTRACT

Staphylococcus aureus ( S. aureus) is one of the most common human pathogens. It has been reported that Panton-Valentine Leukocidin (PVL) as a representative of virulence proteins is an important pathogenic factor for S. aureus infection. However, with the deepening of research, some researchers consider that pvl gene has little effect on the pathogenicity of S. aureus. This article aimed to review and summarize the recent studies on the features, molecular epidemiological characteristics, pathogenicity and controversy of pvl gene.