Association between lung compliance phenotypes and mortality in COVID-19 patients with acute respiratory distress syndrome
Annals of the Academy of Medicine, Singapore
; : 686-694, 2021.
Article
em En
| WPRIM
| ID: wpr-887558
Biblioteca responsável:
WPRO
ABSTRACT
INTRODUCTION@#Acute respiratory distress syndrome (ARDS) in COVID-19 is associated with a high mortality rate, though outcomes of the different lung compliance phenotypes are unclear. We aimed to measure lung compliance and examine other factors associated with mortality in COVID-19 patients with ARDS.@*METHODS@#Adult patients with COVID-19 ARDS who required invasive mechanical ventilation at 8 hospitals in Singapore were prospectively enrolled. Factors associated with both mortality and differences between high (<40mL/cm H@*RESULTS@#A total of 102 patients with COVID-19 who required invasive mechanical ventilation were analysed; 15 (14.7%) did not survive. Non-survivors were older (median 70 years, interquartile range [IQR] 67-75 versus median 61 years, IQR 52-66; @*CONCLUSION@#COVID-19 ARDS patients with higher compliance on the day of intubation and a longitudinal decrease over time had a higher risk of death.
Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Fenótipo
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Síndrome do Desconforto Respiratório do Recém-Nascido
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Complacência Pulmonar
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SARS-CoV-2
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COVID-19
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article