Medullary thyroid carcinoma: a 30-year experience at one institution in Korea
Annals of Surgical Treatment and Research
; : 278-287, 2016.
Article
em En
| WPRIM
| ID: wpr-89529
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: The objective of this study was to review the clinical outcome and prognosis of patients with sporadic and hereditary medullary thyroid cancer (MTC) who were treated at a single tertiary hospital in Korea. METHODS: We retrospectively reviewed the case files of 85 patients treated from August 1982 to February 2012. RESULTS: In all, 65 patients (76.5%) had sporadic MTC and 20 patients (23.5%) had hereditary MTC. Patients in the sporadic group were older than in the hereditary group (P < 0.001). However, the hereditary group had more tumor multiplicity (P < 0.001) and bilaterality (P < 0.001). Neither survival rate was significantly different between the sporadic and hereditary groups (P = 0.775 and P = 0.866). By multivariate analysis, distant metastasis was a significant prognostic factor for overall and progression-free survival. CONCLUSION: In general, patients with MTC have favorable outcomes. Distant metastasis appears to be the strongest predictor of overall and progression-free survival.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prognóstico
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Glândula Tireoide
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Neoplasias da Glândula Tireoide
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Análise Multivariada
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Taxa de Sobrevida
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Estudos Retrospectivos
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Intervalo Livre de Doença
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Centros de Atenção Terciária
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Coreia (Geográfico)
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Metástase Neoplásica
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article