Role of microglia phagocytosis in acute ischemic stroke / 国际脑血管病杂志

ABSTRACT

Microglia, as an inherent immune cell in the brain, is an important defense line against central nervous system injury and participates in the pathogenesis of ischemic stroke. Especially the phagocytosis of microglia plays an important role in the pathogenesis of ischemic stroke. This article reviews the important role and phagocytic mechanism of microglia in acute ischemic stroke, and focuses on the dual effects of its phagocytic function on nerve injury and recovery after stroke, hoping to provide new targets and strategies for microglia-targeted acute ischemic stroke treatment.