TO IDENTIFY SOME RISK FACTOR OF FEMALE INFERTILITY / Шинэ санаа Шинэ нээлт

ABSTRACT

About 10-15% of infertility among reproductive aged couples. According to the Centers for Disease Control, 1/3 of the women among 30 over aged, ½ of the women among 40 over aged women have infertility. Infertility rate is in Europe 10%,in USA 15%, in Russia 17 % (Speroff L. Endocrinology and Infertility. 2005). Female infertility is 45.6%, caused by damage to fallopian tubes is 61%, hormonal causes infertility is 30-40%. In Mongolia the report of study in 1997, infertility rate was 13.06%, report of IVF laboratory of Bayangol hospital infertility rate was 8-10% in 2010, the female infertility was 40-60%. We have first time to study female infertility risk factor among our gynecological department. Aim of study is to identify the some risk factor of female infertility We separated the women into 2 groups by fertile (normal 48 women and infertility 48 women). Hormonal findings was obtained from all women and had survey of questionnaire to risk factor. Statistical analysis did SPSS 20, data were given as mean±SD, the frequencies of the alleles and genotypes in patients and controls were compared with X2 analysis. Odds ratio (OR) and 95% confidence intervals were calculated.The mean age was 33.4±6.1 and mean years of infertility was 7.0±4.5. The primary infertility was 27.1% (n=13), secondary infertility was 72.9% (n=35). The 1.2% (n=15) were given birth, the 33.3% (n=16) had miscarriage and 58.3% (n=28) had abortion of total women. The mean BMI was 24.7±4.6 and 23% were overweight and 13% women were obesity among infertility women. The mean length of uterus was 5.1±1.1 sm, width was 4.0±0.8 sm, mean length of ovaries was 3.1±0.6 sm, mean width was 2.3±0.6 sm among infertility women. Also estradiol mean level was 41.6±22.1 pg/ml, FSH was 15.6±6.1mIU/ml, LH 5.5±1.7mIU/ml, and prolactin 14.4±10.6 ng/ml, progesteron mean level was 0.6±0.1 ng/ml among infertility women. These hormonal level was same in normal women. The risk factor of infertility were sexually transmitted disease (p=0.007, OR=7.667, CI 1.612-36.455), and curettage of uterus (p=0.024, OR=1.357, CI 1.156-1.1819). Secondary female infertility rate was (72.9%) and the women with STD 7.6 hold and women with previous had curettage of uterus will get 1.3 hold the risk of infertility.