The Relationship between Renal Function and Bone Marrow Density in Healthy Korean Women
Journal of Menopausal Medicine
; : 96-101, 2017.
Article
em En
| WPRIM
| ID: wpr-97798
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVES: The relationship between renal function and bone mineral density (BMD) is controversial. We evaluated the relationship between markers of renal function and BMD in healthy Korean women. METHODS: A total of 1,093 women who visited the health promotion center at Pusan National University hospital were included in the cross-sectional study. We divided the study population into two groups by BMD: osteopenia-osteoporosis and normal in the lumbar and femur regions, respectively. We compared the relationship between renal function and BMD using a logistic regression model and used SAS 9.3 (SAS Institute, Inc., Cary, NC, USA) for all statistical analysis. RESULTS: Blood urea nitrogen (BUN), creatinine, and cystatin C (Cys-C) were correlated with BMD in both the normal and osteopenia-osteoporosis groups, and in logistic regression analysis, BUN and Cys-C were correlated with lumbar and femur BMD. However, after we adjusted for age, menopause, and body mass index, only creatinine showed a negative correlation with lumbar BMD, and estimated glomerular filtration rate (eGFR) was related positively with femur BMD. CONCLUSIONS: Serum creatinine could be a marker for lumbar BMD and eGFR for femur BMD in Korean women without overt nephropathy.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Osteoporose
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Nitrogênio da Ureia Sanguínea
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Medula Óssea
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Menopausa
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Índice de Massa Corporal
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Densidade Óssea
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Modelos Logísticos
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Estudos Transversais
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Creatinina
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Cistatina C
Tipo de estudo:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Female
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Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article