Study on expression of the glycoprotein in myocardial cell membrane of the rat's early myocardial ischemic / 法医学杂志

ABSTRACT

OBJECTIVE@#To explore expression of the glycoprotein in early myocardial ischemic.@*METHODS@#The glycoprotein changes occurred at the early acute cardiac ischemic area induced experimentally by ligation of left coronary artery of 32 SD rats. 6 lectins were measured by means of immunohistochemical methods.@*RESULTS@#Positive staining of PNA could be observed in ischemic area at 5 min after ischemia, and the positive area increased with the prolongation of ischemic period. It became the strongest for 2 h and then decreased.@*CONCLUSION@#This experiment proved that myocardial cell membrane in ischemia expressed D-galactose. This may be of some value in forensic medicine practice.