Detalhe da pesquisa
1.
c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease.
Mol Cell
; 56(1): 163-73, 2014 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25219501
2.
Amyloid ß-Peptide Causes the Permanent Activation of CaMKIIα through Its Oxidation.
Int J Mol Sci
; 23(23)2022 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499491
3.
Functionalization of stable fluorescent nanodiamonds towards reliable detection of biomarkers for Alzheimer's disease.
J Nanobiotechnology
; 16(1): 60, 2018 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30097010
4.
Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.
Biochim Biophys Acta
; 1859(2): 269-79, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603102
5.
Peptide multifunctionalized gold nanorods decrease toxicity of ß-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease.
Nanomedicine
; 13(7): 2341-2350, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28673851
6.
Lysosomal vitamin E accumulation in Niemann-Pick type C disease.
Biochim Biophys Acta
; 1822(2): 150-60, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22120593
7.
c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases.
Neural Regen Res
; 18(2): 237-243, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35900397
8.
Differential Detection of Amyloid Aggregates in Old Animals Using Gold Nanorods by Computerized Tomography: A Pharmacokinetic and Bioaccumulation Study.
Int J Nanomedicine
; 18: 8169-8185, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38169997
9.
c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.
Antioxidants (Basel)
; 12(11)2023 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001860
10.
Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease.
Biometals
; 25(4): 777-86, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22526561
11.
Neuronopathic Gaucher disease: Beyond lysosomal dysfunction.
Front Mol Neurosci
; 15: 934820, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35992201
12.
The c-Abl/p73 pathway induces neurodegeneration in a Parkinson's disease model.
IBRO Neurosci Rep
; 13: 378-387, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36590096
13.
c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.
Front Cell Dev Biol
; 10: 844297, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35399514
14.
Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation.
J Neurosci
; 30(10): 3728-38, 2010 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20220006
15.
Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons.
Neurobiol Dis
; 41(1): 209-18, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20883783
16.
Lack of activation of the unfolded protein response in mouse and cellular models of Niemann-Pick type C disease.
Neurodegener Dis
; 8(3): 124-8, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-20714112
17.
c-Abl Kinase Is Required for Satellite Cell Function Through Pax7 Regulation.
Front Cell Dev Biol
; 9: 606403, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33777928
18.
c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning.
Prog Neurobiol
; 205: 102122, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34284000
19.
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage.
Cells
; 10(8)2021 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34440927
20.
p73 participates in male germ cells apoptosis induced by etoposide.
Mol Hum Reprod
; 16(10): 734-42, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20519366