Detalhe da pesquisa
1.
Investigating Sulfoxide-to-Sulfone Conversion as a Prodrug Strategy for a Phosphatidylinositol 4-Kinase Inhibitor in a Humanized Mouse Model of Malaria.
Antimicrob Agents Chemother
; 62(12)2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30249687
2.
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941635
3.
The In Vitro and In Vivo Effects of Hypoxis hemerocallidea on Indinavir Pharmacokinetics: Modulation of Efflux.
Planta Med
; 84(12-13): 895-901, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29672818
4.
In Vitro and In Vivo Pharmacokinetics of Aminoalkylated Diarylpropanes NP085 and NP102.
Antimicrob Agents Chemother
; 60(5): 3065-9, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26953201
5.
Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model.
Malar J
; 14: 8, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25563929
6.
Syntheses and in Vitro Antiplasmodial Activity of Aminoalkylated Chalcones and Analogues.
J Nat Prod
; 78(8): 1848-58, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235033
7.
Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products.
Molecules
; 20(12): 22113-27, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26690396
8.
The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice.
Malar J
; 13: 42, 2014 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24484513
9.
Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355750
10.
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis.
J Med Chem
; 64(17): 12790-12807, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34414766
11.
Identification of Fast-Acting 2,6-Disubstituted Imidazopyridines That Are Efficacious in the in Vivo Humanized Plasmodium falciparum NODscidIL2Rγ null Mouse Model of Malaria.
J Med Chem
; 61(9): 4213-4227, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29665687
12.
Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies.
J Med Chem
; 60(24): 10118-10134, 2017 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29148755
13.
Evaluation of Isolated Fractions of Aloe vera Gel Materials on Indinavir Pharmacokinetics: In vitro and in vivo Studies.
Curr Drug Deliv
; 13(3): 471-80, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26568138
14.
Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds.
ACS Med Chem Lett
; 4(12): 1198-202, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900630