Detalhe da pesquisa
1.
An in vivo study of the impact of deficiency in the DNA repair proteins PAXX and XLF on development and maturation of the hemolymphoid system.
J Biol Chem
; 295(8): 2398-2406, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915249
2.
Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.
J Exp Med
; 204(7): 1717-27, 2007 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17606631
3.
Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.
Nat Commun
; 13(1): 6618, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36333351
4.
Reduced immunoglobulin class switch recombination in the absence of Artemis.
Blood
; 114(17): 3601-9, 2009 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19692705
5.
An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development.
Elife
; 102021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34519267
6.
Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice.
Front Immunol
; 10: 443, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30923523
7.
PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice.
Cell Death Differ
; 25(2): 444-452, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077092
8.
RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair.
Nat Commun
; 7: 10529, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833222
9.
Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.
Oncogene
; 23(39): 6541-7, 2004 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15221010
10.
Hemizygosity of Nf2 is associated with increased susceptibility to asbestos-induced peritoneal tumours.
Oncogene
; 22(24): 3799-805, 2003 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-12802287
11.
Cernunnos deficiency reduces thymocyte life span and alters the T cell repertoire in mice and humans.
Mol Cell Biol
; 33(4): 701-11, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23207905
12.
DNA repair and the immune system: From V(D)J recombination to aging lymphocytes.
Eur J Immunol
; 37 Suppl 1: S71-82, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17972348
13.
Similar tumor suppressor gene alteration profiles in asbestos-induced murine and human mesothelioma.
Cell Cycle
; 4(12): 1862-9, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16319530
14.
Quinidine impairs proliferation of neurofibromatosis type 2-deficient human malignant mesothelioma cells.
Cancer
; 97(8): 1955-62, 2003 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12673723
15.
Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse.
Genes Dev
; 16(9): 1060-5, 2002 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12000789