[Selected psychological studies in Horton's headache]. / Wybrane badania psychologiczne u chorych z bólem glowy Hortona.

Thirty-one patients with Horton's headaches and a control group of 31 healthy subjects were investigated by means of the 16-factor personality Questionnaire of R. B. Cattell. The group of 31 patients were investigated additionally with the tests of Benton, Bender and the Intelligence Scale Wechsler-Bellevue. Personality questionnaires demonstrated in patients with Horton's headaches a fairly high intensity of factors G and Q4 (frustration of lower needs blocked by higher needs). No changes were found which could suggest presence of cerebral microlesions in the group with Horton's headaches. In the tests for intellectual efficiency the mean results pointed to a slightly above average general intelligence level in patients with Horton's neuralgia and reduced ability of memory, concentration and learning speed.

[Psychological and behavioral predictors of the quality of life of people with multiple sclerosis]. / Psychologiczne i behawioralne wyznaczniki jakosci zycia chorych ze stwardnieniem rozsianym.

The aim of the study was to determine the relationship between some psychological and behavioural variables associated with disease, and health related quality of life. A survey was conducted on a sample of 44 people with multiple sclerosis. Quality of life was defined as life satisfaction and subjective assessment of current health status. The following methods were used: The Satisfaction With Life Scale (Diener et al.) and Visual Analogue Scale (single-item self-ratings of health) to measure the quality of life; Multidimensional Health Locus of Control Scale--MHLC (Wallston et al.); Acceptance of Illness Scale (Felton et al.); Self-Esteem Scale (Rosenberg); Courtauld Emotional Control Scale (Watson and Greer) and Health Behaviour Inventory (Juczynski). A series of step-wise regression models and discriminant function analysis on future quality of life variables were calculated, taking as predictors psychological and behavioural variables. High self-esteem, engagement in a large number of health behaviour and acceptance of illness were most predictive of good health related quality of life of people with multiple sclerosis.

[Use of "rinoflow" inhalation in treatment of paranasal sinusitis]. / Zastosowanie inhalatora "rinoflow" w leczeniu przewleklych zapalen zatok przynosowych.

The inflammatory pathologies of the ENT tract are often characterized by presence of catarral, mucous-purulent and crusty secretions. In such cases, an efficient therapy has to change the dense secretions as first and then remove them. "Rinoflow" is a compressor-micronizer chamber system specially designed for treatment of affections of upper respiratory tract. We used Rinflow in treatment of 62 patients (23 female and 39 male, mean age 42.7 years) with chronic paranasal sinusitis. The results of treatment were estimated by patients, physicians and X-ray examinations. We observed in 37 patients (59.7%) good results after treatment. The use of "rinoflow" was practically effected when the secretions were blocking the natural ostium of paranasal sinuses.

[The value of gastrointestinal antigens in the monitoring of patients with malignant head neoplasms]. / Wartosc antygenu zoladkowo-jelitowego w monitorowaniu chorych na zlosliwe nowotwory glowy.

The authors present the results of examinations of test on the sensitivity of biochemical tumor marker (Ca 19-9) in a group of 35 patients with head malignant tumors. The sensitivity (SE) of Ca 19-9 was 22.9% in preliminary study. The values of Ca 19-9 changed from 22.9% to 25.9% in monitoring of tumors. Positive predictive value (PV+) and specify (SP) were 100% in preliminary study and in monitoring. Negative predictive value (PV-) was 50.9% in preliminary study and 51.6% in monitoring. In 25 patients we observed changes in examined parameters: SE--35%, SP--100%, PV(+)--100%, PV(-)--42.1% in monitoring. Our study indicates that serum levels of Ca 19-9 were higher in patients with head tumors than in control group. The surgical treatment of tumors didn't change the values of Ca 19-9.

[Squamous cell carcinoma antigen for monitoring patients with head neoplasm]. / Antygen raka plaskonablonkowego w monitorowaniu chorych na raka glowy.

The authors present results of evaluation of squamous cell carcinoma antigen (SCC) in 73 persons (35 patients with head carcinoma and 38 healthy persons as control group). We analysed a concentration of SCC in preliminary study and in monitoring, depending on clinical advances of tumour, mass of primary tumour and metastases to lymph nodes. We observed high sensitivity (SE) (63%), high specificity (SP) (97.4%) and predictive values: positive PV(+)--95.6%, negative PV(-)--74% of SCC in preliminary study. These values changed to SE--83.3%, SP--92.3%, PV(+) 90.9%, PV(-)--85.7% in monitoring. Our results indicate that evaluation of SCC have high value in monitoring patients with head carcinoma.

[Alpha-fetoprotein--diagnostic utility in squamous cell carcinoma of the head and neck]. / Alfa-fetoproteina--diagnostyczna uzytecznosc w nowotworach zlosliwych glowy i szyi.

The authors present results of evaluation of alpha-fetoprotein (AFP) in 146 persons (108 patients with head and neck carcinoma and 38 healthy persons as control group). We analyzed a concentration of AFP in preliminary study and in monitoring depending on clinical advances of tumour, mass of primary tumour and metastases to lymph nodes. Our results indicate that evaluation of AFP have not high value in diagnostic procedures and monitoring patients with head and neck carcinoma.

[Diagnostic difficulties in neck tumors]. / Trudnosci diagnostyczne w przypadku guzów szyi.

Neck tumors classification and accessory investigations helpful in diagnosis were presented. An attention was paid to the fact, that not seldom provisional diagnosis appeared to be wrong. Due to exact examination necessity of surgical treatment in some cases was excluded. As a proof of this three clinical cases were demonstrated.

[A rare case of injury of the external auditory meatus]. / Rzadki przypadek urazu przewodu sluchowego zewnetrznego.

The authors present difficulties in the diagnosis and the treatment of rare case of external ear injury. 41-year-old woman with acute inflammation of external ear was observed in our Department. The cause of this inflammation was a foreign body which obliterated the external auditory meatus.

[A case of laryngeal glandular cancer]. / Przypadek raka gruczolowego krtani.

The authors described the rare case of larynx adenocarcinoma. T3 N3 M1 tumor of larynx in 53 years old patients was monitoring by the serum levels of cancer markers: AFP, CEA, Ca 19-9, ferritin, NSE, SCC. High levels of markers were observed.

[Differences in assay sensitivity of selected tumor markers in head and neck neoplasms]. / Róznice czulosçi testów dla wybranych znaczników nowotworowych w raku plaskonablonkowym glowy i szyi.

Serum levels of seven tumor markers (AFP, Ca 19-9, CEA, TPA, NSE, ferritin and SCC-Ag) were measured in 95 patients with carcinoma of the head and neck to determine their sensitivity. The positive rates in 95 patients with the head and neck squamous cell carcinoma (SCC) were: 2.1% for AFP, 13.8% for Ca 19-9, 2.1% for CEA, 32.9% for TPA, 29.8% for ferritin, 53.2% for NSE and 46.8% for SCC-Ag in the first exam. Lowest sensitivity in the first exam of tests were in patients with SCC of the larynx: TPA-29.5%, ferritin-26%, NSE-51%, SCC-Ag 48%. Highest sensitivity of tests were in patients with SCC in other localisation than larynx: AFP-0%, Ca 19-9-23.5%, CEA-5.9%, TPA-38%, ferritin-35%, NSE-56%, SCC-62%. The sensitivity of the combination assay with these four tumor markers (TPA, ferritin, NSE, SCC-Ag) was higher than those obtained with individual markers. The sensitivity of the combination assay was for the group 95 patients 87.4% (first exam), for patients with SCC of the larynx 85.2% (first exam), for 34 patients with SCC in other localisations than larynx 91.2% (first exam). Combination assay with TPA, ferritin, NSE and SCC-Ag could be useful for screening and seems to be most useful for detection of recurrence in the follow-up.

[Tumor markers in monitoring of neoplasms]. / Bichemiczne znaczniki nowotworowe w monitorowaniu chorób nowotworowych.

Prophylaxis, diagnosis, radical treatment and monitoring have a basic significance in the clinic of head cancers. The aim of the clinical course of malignant disease preferred prematurely detection of the recurrence. In the monitoring wide applications have tumor markers. The authors present the results on the sensitivity of seven biochemical tumor markers (AFP, Ca-9, CEA, TPA, NSE, ferritin and SCC) in 42 patients with neoplasm of the head. The sensitivity is for AFP-0%, CEA-10%. Attention was drawn to the relatively high sensitivity for TPA, NSE, ferritin and SCC, particularly for the neoplasms of oral cavity (TPA-45%, NSE-68%, ferritin-38%, SCC-55%) and the pharynx (Ca 19-9-38%, TPA-63%, NSE-62%, ferritin-42%, SCC-83%).

[Rare malignant tumors of the larynx]. / Rzadkie guzy zlosliwe krtani.

The study presents rare neoplasms of larynx. The authors introduce epidemiology, clinical history and medical treatment in two cases of adenocarcinoma and one case of sarcoma. The authors call attention to high malignancy of tumors, early metastases to neck lymph nodes and distant metastases.

[A skull base tumor complicated by rhinorrhea]. / Guz podstawy czaszki powiklany plynotokiem nosowym.

The authors presented a case of rare skull base tumor complicated by rhinorrhoea. Diagnostic procedures and surgical treatment by laryngo-neurosurgical team was described.

[Endoscopic surgery of the sinus: own experiences]. / Chirurgia endoskopowa nosa i zatok przynosowych--doswiadczenia wlasne.

In the Clinic of Otolaryngology Central Clinical Hospital Military School of Medicine in Warsaw in years 1992-1996 there were performed 187 endoscopic operations of nose and paranasal sinuses. Authors analised own material paying particular attention to indications, benefits and failures of these operations. Authors postulate that indications for clinical diagnostic and therapeutic procedures of this technique should be considerably extended in diseases of nose and paranasal sinuses. The application of endoscopic sinus surgery in our Clinic decreased the number of more extended operations of paranasal sinuses.

[A case of objective tinnitus]. / Przypadek obiektywnych szumów usznych.

The authors presented a case of objective tinnitus in patient with glomus tumor suspicion. Tinnitus epidemiology, classification, causes and diagnostic procedure were described. Any organic alterations, which would cause tinnitus, did not find.

[Evaluation of the differences in levels of immunoglobulin G, A,and M in the course of malignant head and neck tumors]. / Ocena róznic stezen immunoglobulin G, A, i M w przebiegu nowotworów zlosliwych glowy i szyi.

Serum levels of a variety of substances shows significant changes in head and neck cancer patients. IgG, IgA, IgM were examined in 100 patients with the head and neck cancer. Serum levels of IgG, IgA and IgM were different in variety localisation of the primary tumor. In patients with head and neck cancer medium serum levels of IgG and IgA were elevated but serum level of IgM was normal. Medium serum levels of IgG and IgA were higher in patients with another cancer than larynx cancer. Medium serum levels of IgM were highest in patients with larynx cancer.

[Squamous cell carcinoma antigen (Scc-Ag): diagnostic utility in squamous cell carcinoma antigen of the head and neck with metastasis to lymph nodes]. / Antygen raka plaskonablonkowego (Scc-Ag): diagnostyczna uzytecznosc w przypadkach nowotworów zlosliwych glowy i szyi z przerzutami do wezlów chlonnych.

Aim of the work was estimation of squamous cell carcinoma antigen (SCC) concentrations in serum and qualification its diagnostic value in patients with malignant neoplasm of head and neck in dependence from presence of metastasis to lymphatic glands. The study comprised the group of 146 persons (108 with head and neck malignant neoplasm, 38 of persons determined group supervisory). At 35 ill one ascertained metastasis to lymph nodes. In presented work sensitivity of SCC in initial investigation was (52.8%), specificity (97.4%), positive predicting value (PV+ = 94.2%) and negative predicting value (PV- = 64.0%). We observed not characteristic statistical dependence of concentrations SCC from presence of metastasis to lymph nodes. There was characteristic correlation between concentration of SCC and presence of metastasis to regional lymphatic glands using of correlation R-Spearman.

[Serum levels of tissue polypeptide antigen in patients with the head and neck cancer according to presence of metastases in lymph nodes]. / Stezenia tkankowego antygenu polipeptydowego u chorych na nowotwory zlosliwe glowy i szyi w zaleznosci od obecnosci przerzutów do wezlów chlonnych.

Aim of the work was estimation of Tissue Polypeptide Antigen (TPA) concentrations in serum and qualification its diagnostic value in patients with malignant neoplasm of head and neck in dependence from presence of metastasis to regional lymph nodes. The study comprised the group of 146 persons (108 with head and neck malignant neoplasm, 38 of persons determined group supervisory). At 35 ill one ascertained metastasis to lymph nodes. In presented work at ill without metastasis to lymphatic glands sensitivity of test TPA carried out 28.8%, and at ill with metastasis 42.9%, attaining 66.7% at ill from N3. One showed, that concentrations TPA grow together from spreading of neoplasm in lymph nodes, and presence of metastasis correlates with concentrations of TPA.

[Gastrointestinal cancer antigen and immunoglobulins G, A, M in patients with head cancer]. / Ocena surowiczych stezen antygenu zoladkowo-jelitowego (Ca 19-9) oraz immunoglobulin G, A, M u chorych z nowotworami zlosliwymi glowy.

The authors present the results of examinations of immunoglobulins A, G, M serum concentrations and of a sensitivity of test of biochemical tumor marker (Ca 19-9) in a group of 35 patients with head malignant tumors. There was a statistically significant increase of immunoglobulins IgA, IgG and decrease of immunoglobulin IgM. We observed statistical correlation between serum concentrations of IgA, IgG and serum concentrations of IgA, IgM. The sensitivity of Ca 19-9 was 23% in the preliminary study. The values of Ca 19-9 changed in monitoring of tumors to 26%. There was a statistically significant correlation between sensitivity of Ca 19-9 and serum concentration of IgM. We did not observe any statistical correlation between Ca 19-9 and the age of patients.

[Retinitis pigmentosa in Kearns-Sayre syndrome resulting from mutation of mitochondrial DNA "de novo"]. / Retinitis pigmentosa w zespole Kearns'a i Sayre'a powstalym w wyniku mutacji DNA mitochondrialnego "de novo".

We present a case of Kearns-Sayre syndrome diagnosed in a boy with retinitis pigmentosa ophthalmoplegia, ancephalomyopathy and cardiomyopathy. A single large-scale mtDNA deletion at very low level in the blood sample using Southern blot analyses and multiprimer DNA amplification was detected. This case demonstrates that retinitis pigmentosa may be due to genetic mitochondrial disturbances.