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1.
Sci Rep ; 13(1): 15538, 2023 09 20.
Artigo em Inglês | MEDLINE | ID: mdl-37730955

RESUMO

One of the significant water-related health challenges globally is due to pollutant fate. Contaminants endanger the lives of humans, animals, and even plants. The present mathematical analysis explains reactive wastewater sludge ejected into a drinking water source from wastewater treatment plants. The assumption that wastewater sludge follows a power-law constitutive relation leads to nonlinear momentum and concentration equations. The contaminants are assumed to follow a nonlinear irreversible first-order sorption model. The numerical solution of the coupled problem is solved using the Bivariate Spectral Local Linearization Method and validated with the spectral Chebyshev weighted residual method. Profiles are presented for dimensionless flow velocity and concentration. Comprehensive explanations for the obtained results are provided with relevant applications.


Assuntos
Água Potável , Poluentes Ambientais , Animais , Humanos , Esgotos , Águas Residuárias , Movimento (Física)
2.
J Biol Dyn ; 14(1): 90-115, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32046615

RESUMO

A mathematical model of malaria dynamics with naturally acquired transient immunity in the presence of protected travellers is presented. The qualitative analysis carried out on the autonomous model reveals the existence of backward bifurcation, where the locally asymptotically stable malaria-free and malaria-present equilibria coexist as the basic reproduction number crosses unity. The increased fraction of protected travellers is shown to reduce the basic reproduction number significantly. Particularly, optimal control theory is used to analyse the non-autonomous model, which incorporates four control variables. The existence result for the optimal control quadruple, which minimizes malaria infection and costs of implementation, is explicitly proved. Effects of combining at least any three of the control variables on the malaria dynamics are illustrated. Furthermore, the cost-effectiveness analysis is carried out to reveal the most cost-effective strategy that could be implemented to prevent and control the spread of malaria with limited resources.


Assuntos
Análise Custo-Benefício , Imunidade , Malária/economia , Malária/imunologia , Modelos Biológicos , Simulação por Computador , Humanos , Malária/epidemiologia , Malária/transmissão , Viagem
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