Detalhe da pesquisa
1.
IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models.
Blood
; 128(23): 2683-2693, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621309
2.
IL1RAP is expressed in several subtypes of pediatric acute lymphoblastic leukemia and can be used as a target to eliminate ETV6::RUNX1-positive leukemia cells in preclinical models.
Haematologica
; 108(2): 599-604, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36226493
3.
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting.
Haematologica
; 103(3): 447-455, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29284680
4.
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Proc Natl Acad Sci U S A
; 112(34): 10786-91, 2015 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26261316
5.
Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib.
Eur J Haematol
; 99(5): 442-448, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28881484
6.
Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
Blood
; 121(18): 3709-13, 2013 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23479569
7.
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
Proc Natl Acad Sci U S A
; 107(37): 16280-5, 2010 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20805474
8.
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML.
Blood Adv
; 7(7): 1204-1218, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383712
9.
Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.
Blood
; 116(12): 2103-11, 2010 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20554971
10.
Clonal competition within complex evolutionary hierarchies shapes AML over time.
Nat Commun
; 11(1): 579, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024830
11.
Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells.
PLoS One
; 12(10): e0186035, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023488
12.
HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects.
Adv Cancer Res
; 88: 1-29, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12665051
13.
FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis.
Leukemia
; 33(9): 2310-2314, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30953031
14.
Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage.
Exp Hematol
; 37(3): 367-75, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19135771
15.
Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome.
Genes Chromosomes Cancer
; 46(7): 635-43, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17394134