Detalhe da pesquisa
1.
Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
Blood
; 135(7): 463-471, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31841594
2.
Effect of itraconazole, food, and ethnic origin on the pharmacokinetics of ivosidenib in healthy subjects.
Eur J Clin Pharmacol
; 75(8): 1099-1108, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31011758
3.
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
J Inherit Metab Dis
; 39(6): 807-820, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27469509
4.
Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia.
Blood
; 121(24): 4917-24, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23641016
5.
Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response.
Blood
; 120(23): 4649-52, 2012 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23074281
6.
HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity.
Toxicol Appl Pharmacol
; 262(1): 1-10, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22676972
7.
Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent histologies: leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma.
Int J Cancer
; 129(8): 1963-9, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21154746
8.
Clinical pharmacokinetics and pharmacodynamics of ivosidenib in patients with advanced hematologic malignancies with an IDH1 mutation.
Cancer Chemother Pharmacol
; 85(5): 959-968, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32296873
9.
Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia.
Leukemia
; 33(11): 2575-2584, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30967620
10.
Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study.
Lancet Gastroenterol Hepatol
; 4(9): 711-720, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31300360
11.
Rhabdomyosarcoma of the maxillary gingiva.
J Periodontol
; 78(9): 1839-45, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17760557
12.
Clinical implications of pathophysiological and demographic covariates on the population pharmacokinetics of trastuzumab emtansine, a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer.
J Clin Pharmacol
; 52(5): 691-703, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21953571
13.
Current issues in adolescent and young adult cancer survivorship.
Cancer Control
; 15(1): 55-62, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18094661
14.
Practical issues of intraoperative frozen section diagnosis of bone and soft tissue lesions.
Cancer Control
; 15(1): 7-12, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18094656
15.
Therapeutic potential of directed tyrosine kinase inhibitor therapy in sarcomas.
Cancer Control
; 15(1): 47-54, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18094660