Detalhe da pesquisa
1.
Intermittent treatment of BRAFV600E melanoma cells delays resistance by adaptive resensitization to drug rechallenge.
Proc Natl Acad Sci U S A
; 119(12): e2113535119, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35290123
2.
Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol O-methyltransferase reaction.
Proc Natl Acad Sci U S A
; 117(20): 10797-10805, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371482
3.
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Nat Methods
; 16(7): 595-602, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249422
4.
Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.
Proc Natl Acad Sci U S A
; 116(31): 15463-15468, 2019 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31311868
5.
Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2.
Biochemistry
; 59(29): 2698-2706, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32643366
6.
Kinase Activation by Small Conformational Changes.
J Chem Inf Model
; 60(2): 821-832, 2020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31714778
7.
Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells.
Mol Cell Proteomics
; 17(4): 550-564, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29255136
8.
Quantitative functions of Argonaute proteins in mammalian development.
Genes Dev
; 26(7): 693-704, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474261
9.
The case of the disappearing drug target.
Mol Cell
; 37(4): 455-6, 2010 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188664
10.
Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma.
Mol Cell
; 34(1): 115-31, 2009 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19362540
11.
Dosage and temporal thresholds in microRNA proteomics.
Mol Cell Proteomics
; 14(2): 289-302, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25467838
12.
A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.
Mol Cell Proteomics
; 14(6): 1599-615, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25850435
13.
Phosphorylation releases constraints to domain motion in ERK2.
Proc Natl Acad Sci U S A
; 111(7): 2506-11, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550275
14.
Dynamics of protein kinases: insights from nuclear magnetic resonance.
Acc Chem Res
; 48(4): 1106-14, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25803188
15.
Slow inhibition and conformation selective properties of extracellular signal-regulated kinase 1 and 2 inhibitors.
Biochemistry
; 54(1): 22-31, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25350931
16.
Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2.
Biochemistry
; 54(28): 4307-19, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132046
17.
The p38ß mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.
J Biol Chem
; 289(34): 23546-56, 2014 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25006254
18.
Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate ß-tubulin folding.
J Biol Chem
; 289(7): 4490-502, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375412
19.
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Nat Genet
; 37(4): 391-400, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15765097
20.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.
Mol Biol Cell
; 35(3): ar31, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117590