Detalhe da pesquisa
1.
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.
Bioorg Med Chem
; 27(3): 457-469, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30606676
2.
Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.
Bioorg Med Chem Lett
; 27(8): 1840-1847, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274633
3.
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B.
J Med Chem
; 63(18): 10188-10203, 2020 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407112
4.
Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients.
J Med Chem
; 57(5): 1812-25, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23547794