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1.
J Med Syst ; 45(2): 16, 2021 Jan 11.
Artigo em Inglês | MEDLINE | ID: mdl-33426595

RESUMO

The fulfillment of unmet needs for contraception can help women reach their reproductive goals. Therefore, there is a growing concern worldwide about contraception and women's knowledge of making an advised choice about it. In this aspect, an outgrown number of apps are now available providing information concerning contraception whether it concerns natural contraception or modern contraception. However, vast amounts of these apps contain inaccurate sexual health facts and non-evidence-based information concerning contraception. On these bases, and in respect to: (1) the needs of women to effectively prevent unintended pregnancies while conducting a stress-free healthy lifestyle. (2) the World Health Organization (WHO) Medical Eligibility Criteria (MEC) for contraception's recommendations, and (3) the results/recommendations of a field study conducted in the reproductive health center 'Les Orangers' in Rabat to collect the app's requirements, we developed an evidence-based patient-centered contraceptive app referred to as 'MyContraception'. Thereafter, we conducted a set of functional tests to ensure that the MyContraception solution is performing as expected and is conform to the software functional requirements previously set before moving to non-functional requirements evaluation. Since customer's feedback is valuable to non-functional testing, we choose to evaluate potential users' feedback. Moreover, giving that mobile app testing is a complex process involving different skill sets, we elaborated a rigorous experimental design to conduct an empirical evaluation of the MyContraception solution, which will exhaustively assess the overall quality of this solution and examine its effects on improving the quality of patient-centered contraception care.


Assuntos
Anticoncepcionais , Aplicativos Móveis , Anticoncepção , Feminino , Humanos , Marrocos , Gravidez , Tecnologia
2.
Comput Methods Programs Biomed ; 184: 105114, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31655305

RESUMO

BACKGROUND: Providing a continuum of care from antenatal, childbirth and postnatal period results in reduced maternal and neonatal morbidity and mortality. Timely, high quality postnatal care is crucial for maximizing maternal and newborn health. In this vein, the use of postnatal mobile applications constitutes a promising strategy. METHODS: A Systematic Literature Review (SLR) protocol was adopted to perform the selection, data extraction and functional evaluation of the available postnatal apps on iOS and Android platforms. The analysis of the functionalities and technical features of the apps selected was performed according to a 37-items assessment questionnaire developed on the basis of the scientific literature of postnatal care and a preliminary analysis of available postnatal apps RESULTS: A total of 48 postnatal apps were retrieved from the app repositories of the iOS and Android platforms. The results of the functional content analysis show that the postnatal apps selected relatively achieved low scores owing to the complexity and the ramification of the postnatal care. CONCLUSIONS: The present study helps in identifying areas related to the postnatal care that require further endeavors to be properly addressed. It also provides directions for developers to leverage the advancement and innovation on mobile technology to build complete and well-suited postnatal apps.


Assuntos
Aplicativos Móveis , Período Pós-Parto , Telemedicina/métodos , Feminino , Humanos , Recém-Nascido , Gravidez
3.
J Med Microbiol ; 67(5): 652-661, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29543148

RESUMO

Purpose. Group B streptococcus (GBS) is an important cause of neonatal sepsis worldwide. Data on the prevalence of maternal GBS colonization, risk factors for carriage, antibiotic susceptibility and circulating serotypes are necessary to tailor adequate locally relevant public health policies.Methodology. A prospective study including pregnant women and their newborns was conducted between March and July 2013 in Morocco. We collected clinical data and vagino-rectal and urine samples from the recruited pregnant women, together with the clinical characteristics of, and body surface samples from, their newborns. Additionally, the first three newborns admitted every day with suspected invasive infection were recruited for a thorough screening for neonatal sepsis. Serotypes were characterized by molecular testing.Results. A total of 350 pregnant women and 139 of their newborns were recruited. The prevalence of pregnant women colonized by GBS was 24 %. In 5/160 additional sick newborns recruited with suspected sepsis, the blood cultures were positive for GBS. Gestational hypertension and vaginal pruritus were significantly associated with a vagino-rectal GBS colonization in univariate analyses. All of the strains were susceptible to penicillin, while 7 % were resistant to clindamycin and 12 % were resistant to erythromycin. The most common GBS serotypes detected included V, II and III.Conclusion. In Morocco, maternal GBS colonization is high. Penicillin can continue to be the cornerstone of intrapartum antibiotic prophylaxis. A pentavalent GBS vaccine (Ia, Ib, II, III and V) would have been effective against the majority of the colonizing cases in this setting, but a trivalent one (Ia, Ib and III) would only prevent 28 % of the cases.

4.
PLoS One ; 11(7): e0158695, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27387665

RESUMO

The relevance of vaginal colonization of pregnant women by Escherichia coli is poorly understood, despite these strains sharing a similar virulence profile with other extraintestinal pathogenic E. coli producing severe obstetric and neonatal infections. We characterized the epidemiology, antimicrobial susceptibility and virulence profiles of 84 vaginal E. coli isolates from pregnant women from Rabat (Morocco) and Manhiça (Mozambique), two very distinct epidemiological settings. Low levels of antimicrobial resistance were observed to all drugs tested, except for trimethoprim-sulfamethoxazole in Manhiça, where this drug is extensively used as prophylaxis for opportunistic HIV infections. The most prevalent virulence factors were related to iron acquisition systems. Phylogroup A was the most common in Rabat, while phylogroups E and non-typeable were the most frequent in Manhiça. Regardless of the apparently "low virulence" of these isolates, the frequency of infections is higher and the outcomes more devastating in constrained-resources conditions, especially among pregnant women and newborns.


Assuntos
Infecções por Escherichia coli/complicações , Escherichia coli/efeitos dos fármacos , Vagina/microbiologia , Antibacterianos/farmacologia , Farmacorresistência Bacteriana , Infecções por Escherichia coli/diagnóstico , Feminino , Infecções por HIV/complicações , Humanos , Testes de Sensibilidade Microbiana , Marrocos , Moçambique , Filogenia , Gravidez , Complicações Infecciosas na Gravidez/microbiologia , Prevalência , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Virulência/efeitos dos fármacos , Fatores de Virulência/metabolismo , beta-Lactamases/uso terapêutico
5.
FEMS Microbiol Lett ; 362(1): 1-4, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25790504

RESUMO

Klebsiella pneumoniae is one of the Gram-negative bacilli most commonly found in urine of pregnant women and causing neonatal sepsis. The aim of this study was to analyse in terms of epidemiology and antimicrobial resistance of 23 K. pneumoniae isolates collected from vaginal swabs or urine of pregnant women, from pharyngeal and ear swabs of apparently healthy newborns and from peripheral cultures and hemocultures of newborns with suspected invasive neonatal infection in Rabat, Morocco. The prevalence of K. pneumoniae was 0.6 and 0.9% among pregnant women and neonates, respectively. These strains showed lower antimicrobial resistance levels regarding the developed countries. Thus, only one strain from a neonate presented an ESBL. This is the first report of a K. pneumoniae strain causing neonatal sepsis harbouring the blaCTX-M-15 gene in an IncFII plasmid and belonging to ST466 in this area.


Assuntos
Infecções por Klebsiella/epidemiologia , Infecções por Klebsiella/microbiologia , Klebsiella pneumoniae/enzimologia , Klebsiella pneumoniae/isolamento & purificação , Sepse/microbiologia , beta-Lactamases/metabolismo , Sangue/microbiologia , Conjugação Genética , Farmacorresistência Bacteriana , Orelha/microbiologia , Feminino , Transferência Genética Horizontal , Humanos , Recém-Nascido , Klebsiella pneumoniae/classificação , Klebsiella pneumoniae/genética , Testes de Sensibilidade Microbiana , Marrocos/epidemiologia , Tipagem de Sequências Multilocus , Plasmídeos/análise , Gravidez , Complicações Infecciosas na Gravidez/epidemiologia , Prevalência , Urina/microbiologia , Vagina/microbiologia , beta-Lactamases/genética
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