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Int J Mol Sci
; 22(8)2021 Apr 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33924714
RESUMO
Oxidative stress has been postulated as an underlying pathophysiologic mechanism of diabetic retinopathy (DR), the main cause of avoidable blindness in working-aged people. This review addressed the current daily clinical practice of DR and the role of antioxidants in this practice. A systematic review of the studies on antioxidant supplementation in DR patients was presented. Fifteen studies accomplished the inclusion criteria. The analysis of these studies concluded that antioxidant supplementation has a IIB level of recommendation in adult Type 1 and Type 2 diabetes mellitus subjects without retinopathy or mild-to-moderate nonproliferative DR without diabetic macular oedema as a complementary therapy together with standard medical care.
Assuntos
Antioxidantes/administração & dosagem , Antioxidantes/uso terapêutico , Retinopatia Diabética/tratamento farmacológico , Suplementos Nutricionais , Administração Oral , Retinopatia Diabética/diagnóstico , Retinopatia Diabética/epidemiologia , Retinopatia Diabética/fisiopatologia , Humanos , Fatores de Risco
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