Real-Time Arabic Sign Language Recognition Using a Hybrid Deep Learning Model.

Sign language is an essential means of communication for individuals with hearing disabilities. However, there is a significant shortage of sign language interpreters in some languages, especially in Saudi Arabia. This shortage results in a large proportion of the hearing-impaired population being deprived of services, especially in public places. This paper aims to address this gap in accessibility by leveraging technology to develop systems capable of recognizing Arabic Sign Language (ArSL) using deep learning techniques. In this paper, we propose a hybrid model to capture the spatio-temporal aspects of sign language (i.e., letters and words). The hybrid model consists of a Convolutional Neural Network (CNN) classifier to extract spatial features from sign language data and a Long Short-Term Memory (LSTM) classifier to extract spatial and temporal characteristics to handle sequential data (i.e., hand movements). To demonstrate the feasibility of our proposed hybrid model, we created a dataset of 20 different words, resulting in 4000 images for ArSL: 10 static gesture words and 500 videos for 10 dynamic gesture words. Our proposed hybrid model demonstrates promising performance, with the CNN and LSTM classifiers achieving accuracy rates of 94.40% and 82.70%, respectively. These results indicate that our approach can significantly enhance communication accessibility for the hearing-impaired community in Saudi Arabia. Thus, this paper represents a major step toward promoting inclusivity and improving the quality of life for the hearing impaired.

Awareness of undergraduate dental students, interns, and freshly graduated dentists about oral manifestation associated with COVID-19.

OBJECTIVE: There is growing evidence supporting the presence of oral manifestations associated with COVID-19. The study investigates the knowledge of dental undergraduates and recently graduated dentists concerning oral presentations related to COVID-19. METHODS: A cross-sectional descriptive study in Saudi Arabia comprised 305 individuals, including undergraduate dental students, interns, and freshly graduated dentists. Data were collected using a questionnaire disseminated to approximately 500 subjects via WhatsApp groups and other applications. The questionnaire was tested in a pilot study for validity, edited, and validated by 2 supervisors at the College of Dentistry, Qassim University, Buraydah, Saudi Arabia. The questionnaire consisted of questions regarding sociodemographic attributes, the level of expertise of dental practitioners, and their knowledge and perspectives regarding COVID-19 and the implementation of oral lesions interrelated to it. The data was subjected to analysis through the utilization of descriptive statistics and chi-square tests, employing the statistical software SPSS (version 24). RESULTS: About 43.9% of subjects stated that COVID-19 causes oral symptoms. Respondents most frequently reported COVID-19-related dry mouth. Oral ulcers, Candida infection, Hyperpigmentation, tongue coating, atrophy, Petechiae, Herpes, white lesions, Gingivitis, and Periodontitis are further symptoms. COVID-19's oral manifestation was unknown to 41.0% of subjects, and 37.7% of respondents lacked knowledge regarding the most impacted locations of oral manifestations. Oral signs and COVID-19 symptoms are debated and significantly associated with higher educational levels. CONCLUSION: The dental students and freshly graduated dentists in this study have proper knowledge of COVID-19 and its symptoms. Also, most dental students and newly graduated dentists recognize the potential correlation between COVID-19 and oral manifestations with an average to excellent knowledge of the types and sites commonly affected. The level of awareness was associated with higher educational levels.

Evaluation of vincamine against Acetylcholinesterase enzyme.

The current article deals with the in-silico along with enzyme kinetics approach to search for a prominent AChE enzyme inhibitor among the known natural compounds. The computational tools were involved for this purpose and eventual vincamine, a monoterpenoid indole alkaloid, was selected based on several parameters, including free energy of binding (-10.77 kcal/mol) and ADME parameter. Computationally, it confirmed the interaction between vincamine and AChE at an indistinguishable locus from that of substrate AChI (-3.94 kcal/mol) but with much higher binding energy. Interestingly, amino acid residues Gly120, Gly121, Gly122, Glu202, Trp86, Tyr133, Ser203, Phe297, and His447 of AChE were found to be common in these interactions. Further, these findings were approved with wet lab tests where detailed kinetics was studied. It was found that vincamine inhibited AChE with the inhibition constant Ki (239 µM). The value of  IC50 (239 µM) and KM (0.598 mM) was determined and further confirmed by Dixon, Lineweaver- Burk reciprocal, Hanes, and Eadie- Hofstee plots, respectively. The mode of interaction of the compound was found to be competitive for AChE. Thus, the present computational and enzyme kinetics studies conclude that vincamine can be a promising inhibitor of AChE for the effective management of AD.

Seawater Splitting for Hydrogen Generation Using Zirconium and Its Niobium Alloy under Gamma Radiation.

Hydrogen production is produced for future green energy. The radiation-chemical yield for seawater without a catalyst, with Zr, and with Zr1%Nb (Zr = 99% Nb = 1%) were (G(H2) = 0.81, 307.1, and 437.4 molecules/100 eV, respectively. The radiation-thermal water decomposition increased in γ-radiation of the Zr1%Nb + SW system with increasing temperature. At T = 1273 K, it prevails over radiation processes. During the radiation and heat radiation heterogeneous procedures in the Zr1% Nb + SW system, the production of surface energetic sites and secondary electrons accelerated the accumulation of molecular hydrogen and Zr1%Nb oxidation. Thermal radiation and thermal processes caused the metal phase to collect thermal surface energetic sites for water breakdown and Zr 1%Nb oxidation starting at T = 573 K.

A Novel Triazole Schiff Base Derivatives for Remediation of Chromium Contamination from Tannery Waste Water.

Tannery industries are one of the extensive industrial activities which are the major source of chromium contamination in the environment. Chromium contamination has been an increasing threat to the environment and human health. Therefore, the removal of chromium ions is necessary to save human society. This study is oriented toward the preparation of a new triazole Schiff base derivatives for the remediation of chromium ions. 4,4'-((1E)-1,2-bis ((1H-1,2,4-triazol-3-yl) imino)ethane-1,2-diyl) diphenol was prepared by the interaction between 3-Amino-1H-1,2,4-triazole and 4,4'-Dihydroxybenzil. Then, the produced Schiff base underwent a phosphorylation reaction to produce the adsorbent (TIHP), which confirmed its structure via the different tools FTIR, TGA, 1HNMR, 13CNMR, GC-MS, and Phosphorus-31 nuclear magnetic resonance (31P-NMR). The newly synthesized adsorbent (TIHP) was used to remove chromium oxyanions (Cr(VI)) from an aqueous solution. The batch technique was used to test many controlling factors, including the pH of the working aqueous solution, the amount of adsorbent dose, the initial concentration of Cr(VI), the interaction time, and the temperature. The desorption behaviour of Cr(VI) changes when it is exposed to the suggested foreign ions. The maximum adsorption capacity for Cr(VI) adsorption on the new adsorbent was 307.07 mg/g at room temperature. Freundlich's isotherm model fits the adsorption isotherms perfectly. The kinetic results were well-constrained by the pseudo-second-order equation. The thermodynamic studies establish that the adsorption type was exothermic and naturally spontaneous.

Polyaniline Modified CNTs and Graphene Nanocomposite for Removal of Lead and Zinc Metal Ions: Kinetics, Thermodynamics and Desorption Studies.

A novel polyaniline-modified CNT and graphene-based nanocomposite (2.32-7.34 nm) was prepared and characterized by spectroscopic methods. The specific surface area was 176 m2/g with 0.232 cm3/g as the specific pore volume. The nanocomposite was used to remove zinc and lead metal ions from water; showing a high removal capacity of 346 and 581 mg/g at pH 6.5. The data followed pseudo-second-order, intraparticle diffusion and Elovich models. Besides this, the experimental values obeyed Langmuir and Temkin isotherms. The results confirmed that the removal of lead and zinc ions occurred in a mixed mode, that is, diffusion absorption and ion exchange between the heterogeneous surface of the sorbent containing active adsorption centers and the solution containing metal ions. The enthalpy values were 149.9 and 158.6 J.mol-1K-1 for zinc and lead metal ions. The negative values of free energies were in the range of -4.97 to -26.3 kJ/mol. These values indicated an endothermic spontaneous removal of metal ions from water. The reported method is useful to remove the zinc and lead metal ions in any water body due to the high removal capacity of nanocomposite at natural pH of 6.5. Moreover, a low dose of 0.005 g per 30 mL made this method economical. Furthermore, a low contact time of 15 min made this method applicable to the removal of the reported metal ions from water in a short time. Briefly, the reported method is highly economical, nature-friendly and fast and can be used to remove the reported metal ions from any water resource.

Postpartum Depression Prevalence and Associated Factors: An Observational Study in Saudi Arabia.

Background and Objectives: Postpartum depression (PPD) is a psychological disorder in women who recently gave birth. It can present as mild to severe depression. Multiple studies across the globe have used the Edinburgh Postnatal Depression Scale to reveal the factors that affect the prevalence of PPD. Results from various published studies showed a high prevalence of PPD in Saudi Arabia. The objective of this study is to investigate the major factors that increase PPD and other associated factors. Materials and Methods: An observational cross-sectional study was carried out at primary healthcare centres and military hospitals in Al Kharj. The study measured the rate of PPD among Saudi women during the postpartum period. We studied 279 women aged 19-45 (mean age 31.91, SD ± 6.45) in their postpartum period and followed up to 2 months after delivery. Results: The prevalence of PPD in our cohort was 32.8%. Multivariate logistic regression analysis showed that previous depression diagnosis (p = 0.001), lower education status (p = 0.029), unemployment (p = 0.014), and delivery disposition of C-section (p = 0.002) remained associated with an increased risk of developing PPD. Conclusions: The increasing number of Saudi women with PPD demonstrates that it is a highly prevalent condition. PPD affects not only the health of the mother but also that of her baby and other family members. Our results showed that the history of diagnosed depression, lower education status, unemployment, and delivery disposition of C-sections were independent predictors of PPD development. Raising awareness and controlling the vulnerable factors could decrease the high risk of its effects.

Comparison of subtalar mobilisation with conventional physiotherapy treatment for the management of plantar fasciitis.

OBJECTIVES: To compare the effectiveness of subtalar mobilisation technique on pain and functional disability compared to conventional physiotherapy in patients with plantar fasciitis. METHODS: The randomised controlled trial was conducted at the Prime Care Hospital, Faisalabad, Pakistan, from January to August 2017, and comprised patients of either gender aged 30-60 years presenting with complaints of heel and foot pain, a limited range of motion at the ankle joint due to heel pain, and pain in the morning when taking the first steps or after prolonged rest. The participants were randomly assigned to intervention group A, that received subtalar mobilisation, and control group B treated with therapeutic ultrasound. The groups received two treatment sessions per week over 3 weeks. Patients in both the groups received stretching and rigid tapping as standard treatment. Visual analogue scale and the foot and ankle disability inventory were used to measure pain and functional disability. Data was analysed using SPSS 20. RESULTS: Of the 60 patients enrolled, 8(13.3%) were lost to follow-up, while 52(86.6%) completed the study. Of the 52 subjects, there were 25(48%) in group A with a mean age of 32.40±8.02 years, while in group B there were 27(52%) subjects with a mean age of 32.59±7.00 years. Group A had 11(44%) males and 14(56%) females, while group B had 16(59.3%) males and 11(40.7%) females. Mean body mass index for group A was 25.35±3.8 compared to 25.67±3.25 for group B. There were significant differences in terms of pain between the two groups (p<0.05). Group A showed more reduction in functional disability than group B (p<0.05). CONCLUSIONS: Subtalar mobilisation with movement was found to be effective in reducing pain and functional disability than conventional treatment in patients with plantar fasciitis. RANDOMIZED CONTROLLED TRIAL NO: 20200221046567N2 dated April 18, 2020. URL:https://www.irct.ir/trial/46988.with the World Health Organisation (WHO)-recognised Iranian Registry of Clinical Trials.

Bovine jugular vein valved xenograft for extracardiac total cavo-pulmonary connection: The risk of thrombosis and the potential liver protection effect.

BACKGROUND: Currently, non-valved conduits are preferred for extracardiac total cavo-pulmonary connection (TCPC). However, previous work has failed to provide objective data comparing the postoperative outcome between non-valved TCPCs and bovine jugular vein valved xenograft (BJV) TCPCs. Hence, the objective of this study is to compare the postoperative outcomes in extracardiac TCPC patients who received BJV vs synthetic non-valved conduits and evaluate the effect of BJV on liver fibrosis. METHODS: Of 206 patients who had extracardiac TCPC from 2002 to 2017 were divided into three groups. Group A (n = 66) received BJV, group B (n = 37) received PET conduits and group C (n = 103) received polytetrafluoroethylene (PTFE) tube. Study endpoints were hospital outcomes, conduits thrombosis, reinterventions, and survival. Liver stiffness and fibrosis were assessed in eight patients with BJV. RESULTS: Preoperative parameters were comparable among groups. Thrombosis was significantly lower in group C (P < .0003) but no difference between groups A and B (P = .951). Reinterventions did not differ significantly among groups (Log-rank P = .598). Hospital deaths occurred in seven patients (3.4%). There was no difference in survival between groups (Log-rank P = .221). The median liver stiffness score was 18.65 kPa and the eight patients had advanced liver fibrosis (grade F3-4) in group A. CONCLUSION: PTFE is the recommended conduit for TCPC with a lower risk of thrombosis compared to BJV and PET. BJV conduits in TCPC circuits may not protect against liver fibrosis. BJV should not be considered as an option for TCPC.

Clinical evaluation of two types of intracorneal ring segments (ICRS) for keratoconus.

PURPOSE: To compare the outcome measures following implantation of two types of ICRS. METHODS: Forty-four eyes of keratoconic patients (aged 18-50 years) were randomly assigned to femtosecond laser-assisted Keraring ICRS (Group A) or MyoRing (Group B) implantation. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, keratometry (K), and aberrations were compared preoperatively, at 3 and 6 months postoperatively. A survey was conducted to assess patient's satisfaction, 6 months postoperatively. RESULTS: In Groups A (n = 26) and B (n = 18), UDVA was increased (P < 0.05), but CDVA increased only in Group A (P < 0.05) 6 months postoperatively. The mean K was reduced by 4.55 D (P < 0.0001) in Group A and 6.51 D (P < 0.001) in Group B. Six months postoperatively, the mean refraction spherical equivalent (MRSE) decreased by 2.90 and 3.60 D in Groups A and B, respectively (P < 0.0001). Between groups, coma was more reduced (P = 0.035) in Group B than A, 6 months postoperatively. On motivation for surgery, 88.9% of patients' ranked "desire to improve unaided vision" and "relief from glasses" (77%) topmost. Seventy-seven (77%) of Group A and 89% of Group B patients were satisfied with their unaided vision at the final visit, after 6 months. CONCLUSIONS: KeraRing (A) and MyoRing (B) corneal implants both performed well in improving vision and stabilising the cornea. Implantation of the MyoRing caused greater reduction in coma and better patient satisfaction, but CDVA improved only in the Keraring group, at the final visit.

Myopia control during orthokeratology lens wear in children using a novel study design.

PURPOSE: To investigate the effect of overnight orthokeratology (OK) contact lens wear on axial length growth in East Asian children with progressive myopia. DESIGN: A prospective, randomized, contralateral-eye crossover study conducted over a 1-year period. PARTICIPANTS: We enrolled 26 myopic children (age range, 10.8-17.0 years) of East Asian ethnicity. METHODS: Subjects were fitted with overnight OK in 1 eye, chosen at random, and conventional rigid gas-permeable (GP) lenses for daytime wear in the contralateral eye. Lenses were worn for 6 months. After a 2-week recovery period without lens wear, lens-eye combinations were reversed and lens wear was continued for a further 6 months, followed by another 2-week recovery period without lens wear. Axial eye length was monitored at baseline and every 3 months using an IOLMaster biometer. Corneal topography (Medmont E300) and objective refraction (Shin-Nippon NVision-K 5001 autorefractor) were also measured to confirm that OK lens wear was efficacious in correcting myopia. MAIN OUTCOME MEASUREMENTS: Axial length elongation and myopia progression with OK were compared with conventional daytime rigid contact lens wear. RESULTS: After 6 months of lens wear, axial length had increased by 0.04±0.06 mm (mean±standard deviation) in the GP eye (P=0.011) but showed no change (-0.02±0.05 mm) in the OK eye (P=0.888). During the second 6-month phase of lens wear, in the OK eye there was no change from baseline in axial length at 12 months (-0.04±0.08 mm; P=0.218). However, in the GP eye, the 12-month increase in axial length was significant (0.09±0.09 mm; P<0.001). The GP lens-wearing eye showed progressive axial length growth throughout the study. CONCLUSIONS: These results provide evidence that, at least in the initial months of lens wear, overnight OK inhibits axial eye growth and myopia progression compared with conventional GP lenses. Apparent shortening of axial length early in OK lens wear may reflect the contribution of OK-induced central corneal thinning, combined with choroidal thickening or recovery due to a reduction or neutralization of the myopiogenic stimulus to eye growth in these myopic children.

Investigation of tear osmolarity using the TearLab Osmolarity System in normal adults in Saudi Arabia.

OBJECTIVES: To investigate the repeatability and average tear osmolarity using the new lab-on-chip TearLab technology device in normal subjects living in Saudi Arabia, a hot climate country, and to compare the average readings with data from previous studies. METHODS: Thirty healthy young adults (13 males and 17 females) who ranged in age from 20 to 40 years (mean±SD: 28.57±5.58 years) with no symptoms of dry eyes or ocular disease, who did not wear contact lenses, and were not pregnant or breastfeeding were enrolled in the study. For inclusion criteria, all subjects were examined under a slit-lamp to verify the absence of ocular surface disorders. Moreover, phenol red thread, tear breakup time (TBUT) tests, and McMonnies questionnaire were used to exclude dry eyes. Three measurements of tear osmolarity were performed in 1 eye (at 5-min intervals) using the TearLab osmometer. RESULTS: The mean score on the McMonnies questionnaire was 6±2.9. The mean values obtained from the phenol red thread and TBUT tests were 22±7.7 mm (OD), 21.5±6.6 mm (OS) and 12±1.7 s (OD), 12.5±1.6 s (OS), respectively. There were no statistically significant differences between the osmolarity readings (Wilks' lambda; P=0.945). Tear osmolarity results confirmed that 50% of subjects had readings of 299 to 312 mOsm/L, 40% had readings of 288 to 299 mOsm/L, and 10% had readings of 277 to 288 mOsm/L. The overall mean osmolarity was 299.06±7.65 mOsm/L. There was a medium correlation between osmolarity and the McMonnies questionnaire and a strong negative correlation between osmolarity and TBUT values. CONCLUSIONS: We found that the average osmolarity for subjects living in Saudi Arabia was 299.06±7.65 mOsm/L, which falls within the reference range and is in agreement with published results (298.0-301.9±7.2-16.0 mOsm/L). Osmolarity was positively correlated with McMonnies questionnaire and negatively correlated with TBUT values. The TearLab osmolarity system test showed good precision in repeated measurements. This is the first report of use of the TearLab osmolarity system to assess tear film in normal Saudi adults.

Comparative study of repeatability of phenol red thread test versus Schirmer test in normal adults in Saudi Arabia.

OBJECTIVE: To investigate the repeatability of the phenol red thread (PRT) and Schirmer tests in healthy Saudi adults. Additionally, we compared the PRT mean value with those reported previously because of significant differences between Hong Kong-Chinese, Japanese, and US subjects. METHODS: Thirty healthy young Saudi adults (7 men and 23 women; 60 eyes) with a mean age of 22.37±2.31 years were recruited. Participants provided consent and completed a McMonnies questionnaire. Dry eye subjects were excluded based on this questionnaire and slit-lamp examination. Both eyes of each subject were examined using the PRT and Schirmer tests. Each test was repeated three times for each eye, five minutes apart. The PRT test was applied first, followed by the Schirmer test 15 minutes later under anesthesia to avoid any inconsistency of the measurements due to reflex tears. RESULTS: The PRT and Schirmer tests both demonstrated good repeatability with no statistically significant differences. There was a poor correlation between the 2 tests (r=0.286). There was no statistically significant difference between OD and OS in the two tests. The mean PRT values in normal Saudi subjects were higher than those reported previously for Hong Kong-Chinese, Japanese, and US subjects. CONCLUSIONS: Both the PRT and Schirmer tests displayed good repeatability; however, there was a poor correlation between the tests, as reported previously. The mean PRT value in normal Saudis was higher, when compared with those reported previously for other ethnic groups.

Pediatricians' Awareness of Pediatric Psoriasis in the Makkah Region, Saudi Arabia.

Background Psoriasis is an autoimmune disease characterized by the typical appearance of red, thickened, scaly patches on the skin (plaques). These plaques can vary in size and distribution from person to person. In some individuals, it may affect small areas of skin, while in others, large areas covering their body may be involved. Patients with psoriasis might be identified by pediatricians before being seen by dermatologists, highlighting the need for pediatricians to be aware and knowledgeable about pediatric psoriasis. Objective To evaluate the knowledge and management of pediatric psoriasis among pediatricians and pediatric residents in the Makkah region, Saudi Arabia. Methods This was a cross-sectional study using a questionnaire targeted at pediatricians. It inquired about sociodemographic details, knowledge of psoriasis risk factors, diagnosis, management, comorbidity screening, and indications for consulting a dermatologist. The knowledge score cut-off was set at 60%, with scores below this threshold considered indicative of poor knowledge and scores above it reflecting good knowledge. Results A total of 139 participants completed the questionnaire; 103 (74.1%) were from Jeddah, 101 (72.7%) were pediatric residents, 118 (84.9%) were general pediatricians, and 18 (15.1%) were in subspecialties. About a third, 49 (35.3%), reported having seen a child with psoriasis. Most participants, 84 (60.4%), had a good knowledge level regarding psoriasis. The vast majority, 119 (85.6%), stated that topical therapies are the first-line treatment; 105 (75.5%) reported being confident in diagnosing psoriasis, and having previously seen a patient with psoriasis was associated with certainty in diagnosis (p-value=0.048); 82 (59%) referred patients to dermatologists. Physician position (p-value=0.049) and being in a general specialty (p-value=0.048) were associated with higher knowledge. Conclusion Overall, participants had good knowledge of pediatric psoriasis and its management. However, there is still a need for improvement.

Retraction: Bilateral Elastofibroma Dorsi: A Case From General Practice.

[This retracts the article DOI: 10.7759/cureus.21315.].

Efficient Adsorption and Removal of the Herbicide 2,4-Dichlorophenylacetic Acid from Aqueous Solutions Using MIL-88(Fe)-NH2.

Metal-organic frameworks (MOFs), a material known for its multifunctionality, chemical stability, and high surface area, are now commonly utilized as an adsorbent for water treatment. The MOF (MIL-88(Fe)-NH2) was synthesized and used to remove the commonly used toxic herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) from water. The MIL-88(Fe)-NH2 MOF was fully characterized using multiple techniques. A systematic investigation was conducted to evaluate the key parameters that impact the adsorption process, which include coexisting anions, adsorbent dosage, and solution pH. The adsorption isotherm was fitted using the Langmuir model, while the kinetics were fitted using pseudo-second-order. The adsorption process was both chemisorption and endothermic. The capacity for adsorption increased with rising temperatures. The MIL-88(Fe)-NH2 adsorbent has a maximum adsorption capacity of 345.25 mg g-1 for removing 2,4-D, significantly higher than previous adsorbents used for this purpose. The adsorption mechanism could be ascribed to hydrogen bonding, pore filling, π-π conjugations between the 2,4-D molecules and the MIL-88(Fe)-NH2 adsorbent, and electrostatic interactions. Furthermore, the adsorption capacity of MIL-88(Fe)-NH2 adsorbent showed only a slight decrease after five successive recycles, and it could be easily regenerated through solvent washing. When used in environmental water samples, especially those containing electronic wastes, the MIL-88(Fe)-NH2 adsorbent demonstrated satisfactory adsorption capacity and reusability. The MIL-88(Fe)-NH2 adsorbent is more practical and reusable and has better adsorption capacity and shorter equilibrium time compared to previously reported adsorbents.

Choroidal thickness measurements in young Saudi adult population: a cross-sectional study.

AIM: To determine the choroidal thickness (CT) in young healthy Saudi adults using spectral-domain optical coherence tomography (SD-OCT) with an automated CT segmentation software. METHODS: Fifty-eight young adults (total of 116 eyes), 39 males and 19 females participated in this study between the ages of 18 and 38y (mean 22.65±3.9y). All participants underwent ophthalmic screening examination, including the SD-OCT for measurements of CT in each quadrant egmented into five eccentric regions starting from the foveal region up to 4.5 mm towards the periphery. RESULTS: The choroid was thickest in the foveal region (central 1 mm, 300±60 µm) and began to progressively thinner beyond the parafovea (1.5-2.5 mm, 284±67 µm) towards the peripheral region (3.5-4.5 mm from the fovea, 254±83 µm). The superior choroid showed the thickest profile (309±57 µm), while the nasal choroid exhibited the thinnest (229±76 µm). The rate of the thinning with increasing eccentricity was more predominant in the nasal choroid, which thinned from the foveal region (294±58 µm) to the peripheral region (158±55 µm). The superior and inferior choroid did not show a statistically significant thinning with eccentricity (all P>0.05). There was no statistically significant difference in the CT between gender, age, and laterality of the eyes (all P>0.05). A significant association of myopia with thinner subfoveal choroid was observed (Pearson's, r=0.37), and regression analysis showed that a 10.3 µm choroidal thinning for each diopter increase of myopia. CONCLUSION: CT profile depends on eccentric and the quadrant. The CT profile across the measured area in the young Saudi adult population is comparable to other previous reports. Refractive error is critical for CT evaluation.

The Prevalence of Electronic Cigarette Use Among College Students of Taibah University and Symptoms of Cardiovascular Disease.

Background: Electronic cigarettes (e-cigarettes) have been increasing in popularity among young adults due to the misconception about the safety of e-cigarettes. Our study aims to identify the prevalence rate of e-cigarette use among college students, the reason behind their use, and the relationship between the use of electronic cigarettes and cardiovascular symptoms among college students. Methods: An online questionnaire was sent to students of Taibah University between 2021 and 2022. Data from this survey were analyzed to obtain the prevalence of e-cigarette use among Taibah University students and to compare the demographic and health characteristics differences between e-cigarette users and non-users. The prevalence of cardiovascular symptoms was also compared between the two groups. Results: A total of 519 students participated in this study. The prevalence rate of e-cigarette use was 24%. Compared to non-users, e-cigarette users were more likely to be male (71% vs. 40%, p < 0.01), overweight (44% vs. 32%, p = 0.01), and drug users (4% vs. 1%, p = 0.01). E-cigarette users were likelier to complain of cardiovascular symptoms, including chest pain (19% vs. 10%, p = 0.01), shortness of breath (14% vs. 7%, p = 0.02), and palpitation (12% vs. 6%, p = 0.03). The association between e-cigarette use and cardiovascular symptoms was significant even after adjusting for students' characteristics. Students' main reasons for e-cigarette use were to enjoy the flavors of e-cigarettes, quit tobacco smoking, and improve depression. Conclusion: The prevalence rate of e-cigarette use among college students was 24%. The self-reported cardiovascular disease symptoms rate was doubled among e-cigarette users compared to non-users.

Assessing awareness and knowledge level of clubfoot among a rural city population in Saudi Arabixsa: A cross-sectional study.

Purpose: Clubfoot is among the most common musculoskeletal congenital anomalies. Poor understanding of clubfoot can cause lack of awareness that leads to complications in treating this condition because of late medical intervention. This is considered as a significant public health problem, especially in communities where the burden of clubfoot deformity remains unrecognized. We assessed the level of awareness and knowledge on clubfoot among residents of rural areas and determined the knowledge and attitudes of the public toward the risk factors and general consequences of clubfoot. Methods: This cross-sectional study, conducted from January to July 2021, included the general population of small city and rural area residents. The participants completed a self-administered survey on the web. The questionnaire was pre-tested in a pilot study to ensure comprehension and ease of administration. Results: Altogether, 41.6% of the participants recognized the scientific name of clubfoot in their native language, whereas 38.9% identified the disorder after they were shown a photograph of it. The most recognized risk factors of clubfoot according to the participants were family history (52.2%), complicated pregnancy (46.5%), and medications (43.4%). Only 8.8% of the participants considered casting the initial treatment of clubfoot. Conclusion: An individual's residential area plays a role in their level of awareness concerning clubfoot. Our results suggest that many educational interventions for clubfoot must be provided in rural areas, particularly regarding therapeutic options and plans of care.

Correlation and Factors Influencing Knee Pain Status among Patients who Underwent Sleeve Gastrectomy in Saudi Arabia: A Cross Sectional Study.

Objective: The goal of this study was to see if there was a link between individuals who had a sleeve gastrectomy and their knee discomfort, as well as what factors could influence knee pain after a sleeve gastrectomy. Materials and Methods: The general population of Saudi Arabia was studied in this cross-sectional survey, which took place from August 2021 to February 2022. Only people who had had a sleeve gastrectomy and were experiencing knee discomfort were included in the research. Results: The results revealed that bariatric surgery had improved knee pain status in most of the participants (76%) while (12.1%) complained that the pain worsened after the surgery. The results also showed that nearly half of our participants (49.8%) that complain of knee pain have lost more than 35 kg after bariatric surgery, which illustrates the impact of a number of kilograms (kg) lost after bariatric surgery. Only (12.8%) of the participants considered physiotherapy as an intervention for their knee pain. Also, the results showed that severe pain was considerably more prevalent in the older age group and those with concomitant chronic disease. Conclusions: Our data revealed that a small percentage of participants had worsening knee discomfort, which might be connected to inactivity following sleeve gastrectomy surgery. As a result, we urge that further clinical studies be conducted to learn more about the exacerbation of knee pain after a gastrectomy.